A randomised controlled open comparison of azlocillin and gentamicin versus carbenicillin and gentamicin was carried out in patients with cystic fibrosis who were chronically infected with Pseudomonas aeruginosa. The clinical response was assessed by measurements of pulmonary function and of the patients' feelings of wellbeing scored on a visual analogue scale. The sputum penetration of the ant...

A trial was conducted of continuous nebulised salbutamol and oral once a day prednisolone in a group of 11 children with status asthmaticus (group A) and compared with a conventional protocol comprising aminophylline infusion and intravenous hydrocortisone every six hours in a matched control group (group B). Monitoring by a clinical asthma score, pulse oximetry (oxygen saturation, SaO2), and p...

OBJECTIVE The study focused on assessment of the health status of workers during construction phase of highway rehabilitation projects at six selected sites of N5 around Lahore, including Kala Shah Kaku, Muridke, Kamuki, Bhaipheru, Pattoki, and Okara. METHODS The study was based on multi-methods approach involving hazard identification through survey and checklist as well as a questionnaire f...

The diurnal variation (DV) in peak expiratory flow rate (PEFR) has been studied among 132 grain elevator workers who accomplished three daily measurements of PEFR during three weeks. DV was calculated as the difference between the highest and the lowest PEFR as a percentage of the mean PEFR on each day. For the whole group the median was 5.9%. DV was higher among smokers and among workers with ...

BACKGROUND Variability of peak expiratory flow (PEF) has been proposed as a surrogate for bronchial hyperresponsiveness. The normal range of variability of PEF for children has been reported and the test has been used to screen for asthma in population based studies. However, there is little information on the reproducibility of the method in epidemiological settings. METHODS In a cohort stud...

Peak expiratory flow rate (PEFR) was measured in 300 healthy adult male and female staff and students of the University of Benin, Benin City, and the College of Education, Ekiadolor, near Benin. The variations of Peak Expiratory Flow Rate with respect to height (ht), weight (wt) and chest circumference (cc) were determined in these subjects. PEFR values fell within the middle to the lower limit...

peak flow readings begins and hence this measurement is of less diagnostic value. Technically it is quite easy to alter the whistle so that more accurate readings are obtained above 300 1./min., but when this is done the performance of the whistle is less discriminating for small variations at low flow rates. Overestimation of the peak expiratory flow rate by the whistle is negligible (2%). The...

A computer technique (cosinor analysis) has been used to evaluate circadian rhythms in airway calibre in normals and asthmatics. Two hundred and twenty-one normal subjects recorded peak expiratory flow rate (PEFR) at home four times a day for seven days. Rhythm detection was statistically significant in 145 of them (65.6%) who showed a mean amplitude of 8.3% of individual mean PEFR (+/- SD 5.2%...

This study was designed to assess the impact of high particulate concentration on peak expiratory flow rate of lungs of sand stone quarry workers. The workers were engaged in different types of activities such as drilling, loading and dressing. These different working conditions had different concentrations of RSPM, leading to different exposure levels in workers. It was found that exposure dur...

Peak expiratory flow rate (PEFR) was measured in 19 mothers during elective Caesarean section under unsupplemented extradural anaesthesia. In 18 mothers, serial measurements of peak expiratory flow rate indicated adequate expiratory reserve and residual abdominal muscle power consistent with an effective cough. In one mother, with severe respiratory disease, PEFR decreased to a value indicative...