OBJECTIVE to analyze the impact of Pharmacy Intervention (PI), within the healthcare team who manages elderly multi-pathological patients, regarding the evolution of Drug Related Problems (DRPs) and Negative Outcomes Associated with Medication (NOMs). To estimate the prevalence of DRPs, NOMs, and Potentially Inappropriate Prescriptions (PIPs), and the drugs involved, considering the characteris...

If you have ever been a hospital in-patient, you will know what it means to look forward to ward rounds and to fear them at the same time. On the one hand, you lie there hoping for the doctors to come round because you will hear news of your progress, and perhaps whether you can go home. On the other hand, you almost certainly know from experience that the encounter with doctors will be brief a...

Development of prognostic biomarkers for the detection of prenatally damaged neurons before manifestations of postnatal disorders is an essential step for prevention and treatment of susceptible individuals. We have developed a versatile fluorescence reporter system in mice enabling detection of Heat Shock Factor 1 activation in response to prenatal cellular damage caused by exposure to various...

Differential diagnosis of multiple disorders is a challenging problem in clinical medicine. According to the divide-and-conquer principle, this problem can be handled more effectively through decomposing it into a number of simpler sub-problems, each solved separately. We demonstrate the advantages of this approach using abductive network classifiers on the 6-class standard dermatology dataset....

This scientific commentary refers to ‘The development and convergence of co-pathologies in Alzheimer’s disease’, by Robinson et al. (doi:10.1093/brain/awaa438).