Achieving a desirable percutaneous absorption of drug molecule is a major concern in formulating dermatological products. The use of penetration enhancers could provide a successful mean for this purpose. The aim of this study was to evaluate the effect of incorporating a few common penetration enhancers (in different concentrations) into a 0.5% w/w piroxicam (model drug) gel formulation, on th...

achieving a desirable percutaneous absorption of drug molecule is a major concern in formulating dermatological products. the use of penetration enhancers could provide a successful mean for this purpose. the aim of this study was to evaluate the effect of incorporating a few common penetration enhancers (in different concentrations) into a 0.5% w/w piroxicam (model drug) gel formulation, on th...

Background and Aim: Oral bacteria can proliferate in the implant-abutment interface (IAI) and cause inflammation in the peri-implant tissues and adjacent bone. This study aimed to assess the effect of zirconia and titanium abutments on the microleakage of the IAI under oblique cyclic loading conditions. Materials and Methods: In this in-vitro study, 12 implant-abutment assemblies with zirconia...

The first signs of mobile commerce hype are here. Extremely rapid penetration and growth processes are predicted on the basis of some quick descriptions of mobile technology. The roots of these predictions are often found in markets with a low penetration rate of mobile technology. Nevertheless, it should be clear that without real substance in m-commerce products and services the investments i...

This paper gives an overview on the potentials of numerical simulations for understanding dynamics in laser material processing. After a short introduction into the model, simulation results on several processes like laser beam deep penetration welding, drilling or cutting are presented. Furthermore simulation results are compared with experimentally obtained data.

This paper analyzes the impact on mobile telephony diffusion patterns of the two predominant payment regimes, calling party pays (CPP) and receiving party pays (RPP), for mobile termination services. By applying instrumental variable techniques to panel data we account for a possible interdependency of penetration rates and regulatory interventions. For this purpose we use data on political and...

The test approved by the U.S. Food and Drug Administration for assessment of the barrier quality of medical exam gloves includes visual inspection and a water leak test. Neither method tests directly the ability of gloves to prevent penetration by microorganisms. Methods that use microorganisms (viruses and bacteria) to test gloves have been developed but require classical culturing of the orga...

Candida albicans frequently causes superficial infections by invading and damaging epithelial cells, but may also cause systemic infections by penetrating through epithelial barriers. C. albicans is a remarkable pathogen because it can invade epithelial cells via two distinct mechanisms: induced endocytosis, analogous to facultative intracellular enteropathogenic bacteria, and active penetratio...