background and purpose: highly consumption of antibiotics and their entrance into the environment has increased concerns all over the world. these compounds enter to the environment through an incomplete metabolism and a considerable amount of them cannot be removed using usual waste filtration systems. therefore, the present study aimed to investigate the feasibility of using ultraviolet radia...

We have developed a duplex real-time PCR for the rapid diagnosis of Streptococcus pneumoniae infection from culture-negative clinical samples with the simultaneous determination of penicillin susceptibility. The assay amplifies a lytA gene target and a penicillin binding protein 2b (pbp2b) gene target in penicillin-susceptible organisms. The assay was shown to be sensitive (detects 0.5 CFU per ...

BACKGROUND Parenteral penicillin is the first-line regimen for treating syphilis, but unsuitable for some patients due to penicillin allergy and lacking health resources. Unfortunately, the efficacy of penicillin alternatives remains poorly understood. This study aimed to assess the efficacy of ceftriaxone and doxycycline/tetracycline in treating early syphilis relative to that of penicillin, a...

Introduction: The presence of antibiotics due to toxicity and sustainability as well as organic compounds as a combination of hard biodegradable wastewater is an undesirable issue in many industries. The aim of this study was to evaluate the efficiency of dissolved air flotation process for aniline and penicillin G removal from aqueous solutions. Methods: This was an empirical-lab study to w...

EVER since the discovery that penicillin was effective against syphilis efforts have been directed to the limitation of the number of injections to be given by the evolution of preparations which are either more slowly absorbed or more slowly excreted. The. slow absorption methods gained the initiative with the introduction in 1945 of penicillin in oil beeswax (Romansky and Rittman) and the suc...

Several penicillin-producing fungi were examined for ability to produce 6-aminopenicillanic acid (6-APA) and penicillin acylase. 6-APA was found in corn steep liquor fermentations of Trichophyton mentagrophytes, Aspergillus ochraceous, and three strains of Penicillium sp. 6-APA was not detected in fermentations of Epidermophyton floccosum although penicillins were produced. 6-APA formed a large...

The in vitro activities of penicillin and ceftriaxone were compared against 29 strains of Streptococcus pyogenes with the result that ceftriaxone showed greater activity than penicillin. The morphological changes induced by 1/2 and 1x MIC concentrations of penicillin and ceftriaxone, respectively, were very similar using scanning electron microscopy. Competitive binding studies using 'cold' pen...

IN addition to its importance in clinical medicine, the human penicillin allergy system provides a comparatively well defined haptenic system for the study of fundamental immune mechanisms involved in human allergic diseases. Also, the understanding of the mechanisms involved in clinical allergic reactions to penicillin would in turn allow for more rational approaches to the prediction, diagnos...