The cis-trans isomerization of proline serves as a regulatory switch in signaling pathways. We identify the proline isomerase Fpr4, a member of the FK506 binding protein family in Saccharomyces cerevisiae, as an enzyme which binds the amino-terminal tail of histones H3 and H4 and catalyses the isomerization of H3 proline P30 and P38 in vitro. We show that P38 is necessary for methylation of K36...

Industrial process control system due to integration of equipment, existing material and energy recycle streams and their effects are extraordinary importance. The process in terms of safety, product quality and control stability have a challenge when there was defects in a process control system. The isomerization process is gaining importance in the presence of refining context due to upgradi...

In situ measurements of Brønsted acid sites (by titration with 2,6-di-tert-butyl-pyridine) and reduced centers (by UV–vis spectroscopy) were carried out on WOx–ZrO2 with catalysts at 2.9– 32.3 W/nm2 in order to probe how these species form and act as active sites during 2-butanol dehydration. The rate of 2-butanol dehydration (per W-atom) on WOx–ZrO2 reached maximum values at intermediate WOx s...

The purpose of this research is to investigate a zeotropic working fluid mixture in terms of its performance in an organic Rankine cycle (ORC) and the heat transfer characteristics in an air-cooled condenser (ACC). The motivation of this study is that it is well known that the use of a mixture improves the efficiency of an ORC system. However, the behaviour of the mixture in the condensers is n...

We propose a new scheme of the photoactivation and the photobleaching for Dronpa with molecular dynamics method and density functional theory. These processes can be explained by considering cis-trans isomerization in neutral state of chromophore. The proton transfer from anionic to neutral chromophore makes cis-trans isomerization possible via hula-twist rotation process, since the space for c...

Atomistic QM/MM simulations have been carried out on the complete photocycle of Photoactive Yellow Protein, a bacterial photoreceptor, in which blue light triggers isomerization of a covalently bound chromophore. The "chemical role" of the protein cavity in the control of the photoisomerization step has been elucidated. Isomerization is facilitated due to preferential electrostatic stabilizatio...

gamma and (b) alpha cage in zeolite ZK5. 2. Methodology The structure model of the zeolite H-ZK5 was obtained by an optimization using the semi-empirical method MNDO, since no experimental structure data were available. Moreover, the influence of the electric field of the proton has been examined. Two clusters were selected from the optimized zeolite structure, the neutral (Si2O7H6) and the aci...

We examined the role of chemical signals in sex attraction of pear psylla, Cacopsylla pyricola (Förster), assessing the response of summerform male and female psyllids to maleand female-produced volatile chemicals. Male psyllids were attracted to odors from live females and pentane extracts of females. Extracts of females were as attractive to males as live females, suggesting that the female-p...

The low-temperature oxidation of the five hexane isomers (n-hexane, 2-methyl-pentane, 3-methyl-pentane, 2,2-dimethylbutane, and 2,3-dimethylbutane) was studied in a jet-stirred reactor (JSR) at atmospheric pressure under stoichiometric conditions between 550 and 1000 K. The evolution of reactant and product mole fraction profiles were recorded as a function of the temperature using two analytic...

We have simulated the isomerization of 38-atom Lennard-Jones clusters (LJ38) – a well-known prototype system for global-optimization and energy landscape analyses – over a wide range of temperatures using a combination of molecular dynamics (MD) and temperature accelerated dynamics (TAD). At high temperatures, we find that (surprisingly) MD with steepest descent quenches (MDSDQ) is effective fo...