BACKGROUND Contrast induced kidney injury is an acute renal dysfunction that is secondary to the administration of radio contrast media. The purpose of this study was to evaluate the levels of urotensin-II (UT-II) and endothelin-I (ET-I) after contrast media administration in patients undergoing percutaneous coronary interventions. MATERIALS AND METHODS In this prospective cohort study, we ev...

List of abbreviations . . . . . . . . . . . . . . . . . . 2 Preamble: purposes and scope of the task force . . 2 Blood coagulation . . . . . . . . . . . . . . . . . . . . 3 Haemostasis . . . . . . . . . . . . . . . . . . . . . 3 Arterial thrombosis . . . . . . . . . . . . . . . . . 3 Tissue factor . . . . . . . . . . . . . . . . . . . . . 3 Tissue factor pathway inhibitor . . . . . . . . . . 3 ...

Atherosclerosis develops in a patchy, discontinuous fashion within coronary arteries. Therefore, it is possible to treat the discrete areas of obstruction that most impede coronary blood flow to the myocardium. The mechanical approaches to coronary revascularization fall broadly into two categories: coronary artery bypass grafting surgery (CABG) and catheterbased percutaneous coronary intervent...

Percutaneous treatment of complex coronary bifurcation lesions is a constant challenge for the interventionist. Bifurcation lesions are frequent, representing 15% to 20% of all percutaneous coronary interventions (PCIs). Their treatment is associated with lower procedural success and a higher incidence of periprocedural myocardial infarction, stent thrombosis and in-stent restenosis, as well as...

BACKGROUND Women with acute myocardial infarction have a higher hospital mortality rate than men. This difference has been ascribed to their older age, more frequent comorbidities, and less frequent use of revascularization. The aim of this study is to assess these factors in relation to excess mortality in women. METHODS AND RESULTS All hospital admissions in France with a discharge diagnosi...

The management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and/or undergoing percutaneous coronary inter vention/stenting cannot be done according to a regimented common protocol, and stroke and bleeding risk stratification schema should be employed to individualize treatment options. A delicate balance is needed between the prevention of th...

conclusion: although timi grade 3 flows trended to be higher in the patients who received early tirofiban in the emergency ward, the difference did not constitute statistical significance and possible benefits, therefore, require further clarification. results: the study population had a mean age of 57.17 ± 10.09 years and included 79.3 % males. timi grade 3 flow was seen in 15 (21.4 %) patient...

Inadequate hemostasis and bleeding are frequent complications after surgical procedures and medical interventions (for example, after a percutaneous heart catheterization). To stop bleeding during coronary interventions, in addition to mechanical arteriotomy closure devices, many products are used that aid manual compression and/or activate the coagulation cascade. The goal of this study was to...