INTRODUCTION ST2 is a member of the interleukin (IL)-1 receptor family, and IL-33 is its natural ligand. ST2 signaling promotes Th2 immune response in allergy, autoimmunity, and chronic inflammatory disorders, but its role in the pathogenesis of periapical lesions is unknown. The purpose of this study was to investigate whether ST2 gene deletion affects the development of experimentally induced...

Traumatic injuries commonly affect the anterior teeth leading to slow death of the pulp. This may give rise to a periapical or radicular cyst which results from the proliferation of cell rests of Malassez following pulpal necrosis of a nonvital tooth. This condition is usually asymptomatic but can result in a slow-growth tumefaction in the affected region. On radiography the lesion can be seen ...

In teeth with periapical lesions and defective root canal seals non-surgical retreatment is usually preferred. Sometimes, however, such treatment may not be feasible and periapical surgery must be performed. The present study investigated a technique of retrograde root canal treatment as an alternative to the more conventional types of surgical procedure. The material consisted of 35 teeth whos...

Although periapical inflammatory lesions are usually resulted by infection in the root canal system, this rare case showed that a periapical lesion related to an infected tooth may cause pulpal necrosis in adjacent intact tooth, with no history or clinical signs of caries, disease, trauma or developmental anomaly. This case also suggests that the periapical lesion can be treated conservatively,...

A customized acrylic-resin template with gutta percha markers was fabricated for a human cadaver mandible. Twelve measurements were made between gutta percha markers and between the markers and known mandibular anatomic locations. Periapical, panoramic, and computerized tomographic radiographs were taken of the mandible and stent. Similar readings were recorded from the radiographs. The average...

Pulpal and periradicular pathosis are the result of microbial, mechanical, or chemical invasion. Microorganisms are the main irritants of pulpal and periapical tissues. The goal of the obturation is to obtain a fluid-tight seal of the root canal system from its coronal aspect through its apical extent to preserve from the irritants.. Root apices have morphological irregularities in teeth with p...

AIM To determine the pH of pus collected from periapical abscesses. METHODOLOGY Forty patients (Male = 17/Female = 23) between the ages 17 and 37 years, each with a periapical abscess and with no relevant medical history, were recruited. All the participants had moderate-to-severe pain on percussion accompanied by localized or generalized swelling. At least 1 mL of pus was aspirated from each...

Periapical surgery is a well-accepted technique used to salvage endodontically involved teeth that cannot be satisfactorily treated or retreated by nonsurgical conventional endodontic procedures (1-4). Indications for periapical surgery are well described in the above mentioned endodontic references. Considering that the prognosis of success following endodontic surgery ranges from 60 to 89% (5...