Sitafloxacin (STFX) is a newly developed quinolone that has robust antimicrobial activity against periodontopathic bacteria. We previously reported that oral administration of STFX during supportive periodontal therapy was as effective as conventional mechanical debridement under local anesthesia microbiologically and clinically for 3 months. The aim of the present study was to examine the shor...

Introduction: The aim of periodontal treatment is to regenerate periodontium. Regenerative treatments include the use of plasma that is rich in growth factors (PRGF). Materials & Methods: In a randomized clinical trial, 20 three-walled intrabony defects from five patients with moderate periodontitis were randomly assigned to three groups. Patients in the control group underwent debridement of ...

Background and Aim: Lasers can serve as a new powerful tool in dentistry. High intensity laser therapy is becoming the treatment of choice compared with conventional periodontal therapy due to accurate incision and soft and hard tissue ablation, hemostasis, reduction of postoperative pain and infection, optimal debridement, and enhanced healing. Although high intensity laser therapy assumes to ...

statement of the problem subgingival irrigation with an antimicrobial agent after scaling and root planing (srp) is assumed to be able to kill the bacteria left behind after mechanical debridement. 3% h2o2 is used in the treatment of periodontal disease and it has been shown effective in killing anaerobic pathogens. purpose the aim of this study was to evaluate the clinical effects of subgingiv...

Periodontal disease, commonly known as gum disease, affects millions of Americans. The current method of detecting periodontal disease is painful, invasive, and inaccurate. As an alternative to manual probing, the ultrasonographic periodontal probe is being developed to use RF ultrasound waveforms to measure periodontal pocket depth, which is the main measure of periodontal disease. The methods...

Salivary IgA can serve as a first line of defense against pathogens that colonize and invade mucosal surfaces and may be protective against periodontal disease. The aim of this study was to assess salivary immunoglobulin A levels in diabetic and non-diabetic patients with different periodontal treatment needs. The Periodontal Screening & Recording (PSR) system was used to evaluate the periodont...

OBJECTIVES Despite several investigations, evidence is still controversial regarding the effect of periodontal treatment on diabetes. This study evaluates and compares the effect on glycemic control and periodontal status with or without nonsurgical periodontal therapy in patients with type 2 diabetes mellitus and chronic periodontitis in a Nepalese population. MATERIALS AND METHODS A total o...

AIM We investigated the long-term impact of adjunctive systemic antibiotics on periodontal disease progression. Periodontal therapy is frequently supplemented by systemic antibiotics, although its impact on the course of disease is still unclear. MATERIAL & METHODS This prospective, randomized, double-blind, placebo-controlled multi-centre trial comprising patients suffering from moderate to ...

OBJECTIVES To evaluate the impact of chronic periodontal diseases (PDs) and compare phases of nonsurgical periodontal therapy (NSPT) on oral health-related quality of life (OHRQoL) in patients attending a tertiary care center of eastern Nepal. MATERIALS AND METHODS Matched for socioeconomic status, participants were recruited in two groups: moderate-to-severe chronic periodontitis (n = 24, 43...