Proprioception from masticatory apparatus and periodontal ligaments comes through the trigeminal mesencephalic nucleus (Vmes). We evaluated effects of tooth loss on neurodegeneration Vmes motor (Vmo). Bilateral maxillary molars 2-month-old C57BL/6J mice were extracted under anesthesia. Neural projections to periodontium confirmed by injecting Fluoro-Gold (FG) retrogradely into extraction socket...

Both length of extra-alveolar time and type of storage media are significant factors that can affect the long-term prognosis for replanted teeth. Numerous studies have examined various media in an attempt to determine the ideal material for storage of the avulsed tooth. The purpose of this study was to compare the number of viable periodontium ligament (PDL) cells in different storage media usi...

Regenerative periodontal therapy aims at reconstitution of the lost periodontal structures such as new formation of root cementum, periodontal ligament and alveolar bone. Findings from basic research indicate that enamel matrix protein derivative (EMD) has a key role in periodontal wound healing. Histological results from animal and human studies have shown that treatment with EMD promotes peri...

Proteins are vital parts of living organisms, as they are integral components of the physiological metabolic pathways of cells. Periodontal tissues comprise multicompartmental groups of interacting cells and matrices that provide continuous support, attachment, proprioception, and physical protection for the teeth. The proteome map, that is, complete catalogue of the matrix and cellular protein...

Residual periodontal ligament (PDL) and cement mass on the roots of extracted teeth are factors that considerably affect tooth transplantation. Therefore, when normal extracted teeth are used for autologous transplantation, it is necessary to regenerate the PDL of the root surface. Here we describe a method to examine human PDL cell adhesion on sterilized root surfaces. Sample teeth were extrac...

Natural frequencies and vibration modes of four kinds of teeth were calculated by using a mechanical model. The alveolar bone and the tooth were assumed as rigid bodies, while the periodontal ligament was assumed as an elastic spring. All the natural frequencies were within a range of 1 to 10 kHz. The first natural frequencies of four teeth were about 1.5 kHz, and decreased as the root length d...

Cementum was first described by Denton GB in 1835 as a calcified, avascular mesenchymal tissue that covers the entire root surface. It approximately comprises of 50% of hydroxyappetite and 50% of organic matrix which consist of non collagenous and collagenous proteins. Protein extract of mature cementum promotes cell attachment, migration and stimulates protein synthesis of gingival fibroblast ...

We reported a case of a 10-year-old girl with cementifying fibroma and cementoblastoma co-existed in the right mandible. Her right mandible swelled and became asymmetry in one month. Radiographically, a radiopaqueradiolucent lesion in anterior site and a radiopaque mass in posterior site were revealed. With fibrous dysplasia (anterior lesion) and odontoma (posterior lesion) as our initially dia...

The Hertwig’s epithelial root sheath is a transient structure formed in the early period of root formation. It has an important role in regulation and maintenance of the periodontal ligament space, prevention of root resorption and ankylosis, maintenance of periodontal ligament homeostasis, Induction of acellular cementum formation, as a stem cell in periodontal regeneration and also as a stimu...

Periodontal disease is manifested clinically by a degradation of the ligament that attaches the tooth to the bone. The most widely used diagnostic tool for assessment of periodontal diseases, measurement of periodontal attachment loss with a manual probe, may overestimate attachment loss by as much as 2 mm in untreated sites, while underestimating attachment loss by an even greater margin follo...