The consequences of hypothyroidism on cognition are long known since the description of dementia associated with hypothyroidism. Additional data from experimental studies support the impact of thyroid hormones on the central nervous system and cognition. Cognitive impairment in relation with hypothyroidism (even sub clinical hypothyroidism) in elderly subjects involves memory, attention, and ex...

Hypothyroidism is a common disease, and there may be a link between hypothyroidism and inflammatory skin disease. The purpose of this study is to assess whether hypothyroidism is more prevalent in psoriasis or rosacea patients. We utilized a large claims-based database to analyze rates of hypothyroidism in patients with psoriasis and rosacea compared to other patients with skin diseases. Partic...

BACKGROUND We report the prevalence of coronary artery disease (CAD) associated with subclinical hypothyroidism in older persons. METHODS We investigated the prevalence of subclinical hypothyroidism and its association with dyslipidemia and with CAD in 170 women and 110 men, mean age 75 +/- 9 years, in an academic nursing home. RESULTS Of 280 persons, 18 (6%) had subclinical hypothyroidism,...

Background: Hypothyroidism is associated with dysfunction of the bone turnover with reduced osteoblastic bone formation and osteoclastic bone resorption. Mesenchymal stem cells (MSCs) secrete various factors and cytokines that may stimulate bone regeneration.  The aim of this study was to determine the effects of MSCs-conditioned medium (CM) in hypothyroidism male rats after inducing bone ...

Congenital Hypothyroidism (CH) is one of the common causes of mental retardation in children, which can be easily prevented if diagnosed within a few days after birth. Congenital hypothyroidism is a clinical condition when a baby is born with decreased thyroid hormone production at birth. Hypothyroidism in the newborn, may result from absence or abnormal development of the thyroid gland, destru...

Introduction A endocrine disorders most commonly encountered in the pediatric age group, disorders of the thyroid gland are most frequent with hypothyroidism being the commonest. Goiter (thyromegaly) with or without alterations in thyroid function is not uncommon but hyperthyroidism is less frequent. The most pronounced effect of thyroid dysfunction in this age group is on growth and developmen...

PURPOSE The incidence of congenital hypothyroidism (CH) has increased in several countries. Lower cut-off in screening programs have led to an increase in the proportion of transient hypothyroidism (TH) cases diagnosed, leading to debate on the associated clinical and economic impact. This study aimed to identify factors that would allow discrimination between TH and permanent CH (PH) in patien...

Congenital hypothyroidism (CH) is one of the most common endocrine disorders in the infant population. It is also one of the most important causes of foreseeable brain damage and severe mental impairment. Current views on CH pathogenesis, screening schema and treatment standards have been presented. Also outlined have been the newest reports on the impact on CH epidemiology and classification g...

Congenital hypothyroidism (CH) fulfills all the pre-requisites for being included in a newborn screening (NS) program. It does not present clinical features early and delayed diagnosis has disastrous consequences. Accurate biochemical diagnosis is possible before clinical features set in, and treatment by 2 to 3 weeks of age ensures good outcome. For India, two more important pre-requisites are...

BACKGROUND The aim of this study was to identify the long-term clinical outcome of definitive radiotherapy using three-dimensional conformal radiotherapy (3DCRT) for cervical esophageal squamous cell carcinoma (CESCC). METHODS We retrospectively reviewed the medical records of 30 patients with CESCC [clinical stage I/II/III/IV(M1LYM); 3/2/12/13] (TNM 7th edition) who underwent definitive radi...