نتایج جستجو برای: phage therapy
تعداد نتایج: 671460 فیلتر نتایج به سال:
Phagocytes are the main component of innate immunity. They remove pathogens and particles from organisms using their bactericidal tools in the form of both reactive oxygen species and degrading enzymes-contained in granules-that are potentially toxic proteins. Therefore, it is important to investigate the possible interactions between phages and immune cells and avoid any phage side effects on ...
The aim of this study was to screen for polypeptides binding specifically to LoVo human colorectal cancer cells using a phage-displayed peptide library as a targeting vector for colorectal cancer therapy. Human normal colorectal mucous epithelial cells were applied as absorber cells for subtraction biopanning with a c7c phage display peptide library. Positive phage clones were identified by enz...
Bacteriophages are viruses that attack bacteria. Phage therapy, a method using phages for the treatment of bacterial infectious diseases was introduced by Felix D Herelle, who co discovered phages in 1920. However , with the arrival of the the antibiotic era in the 1940 s it got suppressed, but the ongoing evolution of bacterial multidrug resistance, the potential of phage therapy is again bein...
As the interactions of phage with mammalian innate and adaptive immune systems are better delineated and with our ability to recognize and eliminate toxins and other potentially harmful phage gene products, the potential of phage therapies is now being realized. Early efforts to use phage therapeutically were hampered by inadequate phage purification and limited knowledge of phage-bacterial and...
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