نتایج جستجو برای: phenylalanine inhibition

تعداد نتایج: 341634  

Journal: :Frontiers in sustainable food systems 2023

Fresh-cut taros are prone to browning even though they stored at low temperatures, which leads the quality deterioration and markedly limits shelf life. The control of fresh-cut food with natural substances has received much attention. This study evaluated anti-browning potential peppermint extracts in taro during cold storage. results showed that both leaf shoot extract (LE SE) treatments coul...

Journal: :Catalysts 2021

Phenylalanine ammonia-lyase (PAL) links the plant primary and secondary metabolisms, its product, trans-cinnamic acid, is derived into thousands of diverse phenylpropanoids. Bambusa oldhamii BoPAL4 has broad substrate specificity using L-phenylalanine, L-tyrosine, L-3,4-dihydroxy phenylalanine (L-DOPA) as substrates to yield p-coumaric caffeic respectively. The optimum reaction pH for three was...

Journal: :Catalysts 2022

Trans-cinnamic acid and p-coumaric are valuable intermediates in the synthesis of flavonoids widely employed food, flavor pharmaceutical industries. These products can be produced by deamination L-phenylalanine L-tyrosine catalyzed phenylalanine ammonia lyase or tyrosine lyase. Phenylalanine ammonia-lyase (PAL, EC 4.3.1.5) from Rhodotorula glutinis do not exhibit strong substrate specificity co...

Journal: :The Journal of biological chemistry 1971
T G Obrig W J Culp W L McKeehan B Hardesty

Cycloheximide and related glutarimide antibiotics have been shown to affect binding, transfer enzyme II-dependent movement, and release of transfer RNA from the donor site of reticulocyte ribosomes, as well as both the initiation and extension of globin and phenylalanine peptides. They inhibit binding of deacylated tRNAPhe to reticulocyte ribosomes in the absence of transfer enzymes at concentr...

Journal: :Molecules 2015
Li-Chai Chen Hsiang-Ruei Liao Pei-Yu Chen Wen-Lung Kuo Tsung-Hsien Chang Ping-Jyun Sung Zhi-Hong Wen Jih-Jung Chen

A new limonoid, swietemacrophin (1), was isolated from the seeds of Swietenia macrophylla, together with five known compounds 2-6. The structure of 1 was determined through extensive 1D/2D-NMR and mass-spectrometric analyses. Swietemacrophin (1), humilinolide F (2), 3,6-O,O-diacetylswietenolide (3), 3-O-tigloylswietenolide (4), and swietemahonin E (5) exhibited inhibition (IC50 values≤45.44 μM)...

2005
K. K. KALGHATGI P. V. SUBBA RAO

1. Phenylalanine ammonia-lyase (EC 4.3.1.5) was purified to homogeneity from the acetone-dried powders of the mycelial felts of the plant pathogenic fungus Rhizoctonia solani. 2. A useful modification in protamine sulphate treatment to get substantial purification of the enzyme in a single step is described. 3. The purified enzyme shows bisubstrate activity towards L-phenylalanine and L-tyrosin...

Journal: :The Journal of clinical investigation 1983
L E Rosenthal D J Yamashiro J Rivier W Vale M Brown K Dharmsathaphorn

UNLABELLED Somatostatin increases absorption of electrolytes and inhibits diarrhea in patients with endocrine tumors and short bowel syndrome. In an attempt to develop a gut-specific somatostatin analog, each amino acid in the somatostatin molecule was replaced with L-alanine, deleted, or substituted with its D-isomer. The potency of each analog to stimulate ion transport in the rabbit ileum wa...

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