Concomitant coronary artery disease (CAD) and pheochromocytoma are rare. Patients with advanced CAD requiring coronary artery bypass graft (CABG) surgery and clinically active pheochromocytoma present a challenge to anesthesiologists. The risk is much higher if the patient is an anemic Jehovah's Witness because these patients refuse to receive blood or blood products, even when faced with a lif...

Pheochromocytoma is rare, accounting for less than 0.1 % of hypertensive population. In this report, we describe a 40-year-old male a diagnosed case of pheochromocytoma who underwent adrenalectomy under general anaesthesia with epidural analgesia. The patient was adequately prepared with alpha adrenergic blockers. Intraoperative course was stormy but was managed with antihypertensives, inotrope...

Introduction: Pheochromocytoma is one of the diseases that is known to cause Takotsubo cardiomyopathy, however, because of its rare occurrance a diagnosis of pheochromocytoma may be overlooked in patients with Takotsubo cardiomyopathy. Case Report: We report a case of a patient with Takotsubo cardiomyopathy which was discovered when the patient visited her doctor for consultation for a breast m...

Human pheochromocytoma cells, which are demonstrated to contain and release met-enkephalin and norepinephrine, may be a promising resource for cell therapy in cancer-induced intractable pain. Intrathecal injection of alginate-poly (l) lysine-alginate (APA) microencapsulated human pheochromocytoma cells leads to antinociceptive effect in a rat model of bone cancer pain, and this effect was block...

Pheochromocytomas and Paragangliomas (PGL) form the group of paraganglial tumours which can occur in any paraganglia from the skull base to the pelvic floor. The terminology is not uniform. While the World Health Organization (WHO) applies pheochromocytoma exclusively to adrenal tumours, many clinicians use the term pheochromocytoma also for extra-adrenal abdominal and thoracic tumours, since b...

BACKGROUND Pheochromocytoma is a rare catecholamine-producing tumor with an estimated incidence of less than 0.1% in the global population. We present a case of cystic pheochromocytoma that was diagnosed as an incidental finding. The patient presented with abdominal pain and had a history of hypertension. CASE REPORT A 64-year-old man with hypertension presented with a clinical history of inter...

A pheochromocytoma was maintained in rats from the New England Deaconess Hospital by giving the rats s.c. injections of isolated tumor cells. The animals were sac rificed 3 to 4 weeks after transplantation, the tumors were excised, and purified tumor cells were prepared. Cyclic nucleotide phosphodiesterase of the purified tumor cells was characterized and compared with that of the adrenal medul...

We constructed a human pheochromocytoma cDNA library and used differential hybridization to human pheochromocytoma and human neuroblastoma cDNA probes to isolate genes that are highly expressed in the adrenal medullary neuroendocrine tumor, pheochromocytoma, but not in the more immature embryonal tumor of adrenal medulla, neuroblastoma. Two cDNA clones, pG8 and pG2, were more highly expressed i...

A 54-year-old female presented with a large pancreatic tumor of the tail during a regular physical examination. The patient underwent surgical intervention and the surgeon identified that the tumor originated from the retroperitoneal region. Markedly severe hemodynamic fluctuations occurred during the manipulation of the tumor and continued to occur subsequent to the tumor being removed. The vi...

Multiple Endocrine Neoplasia type IIa (MEN IIa) is an autosomal dominant syndrome characterized by pheochromocytoma, medullary thyroid carcinoma and hyperparathyroidism. Pheochromocytoma occurs in approximately 50% of patients with MEN IIa. This tumor has the capacity to produce ACTH ectopically and manifests as the Cushing syndrome, although it is very rare. We report a 26-year-old woman patie...