The fall in pulmonary compliance in mice with radiation pneumonitis is associated with increased microvascular leakage of plasma proteins into the alveolar spaces and increased surfactant phospholipids in the lung and alveolar fluid. In the present experiments we examined the effect of corticosteroid adminitration on these two effects and on pulmonary mechanics 16 wk after x irradiation of the ...

The sources and mechanisms of gas production by irradiation were determined using model systems prepared with fatty acid, phospholipids, oil, sugars, glycolysis and TCA cycle intermediates, nucleic acids, amino acid monomers and homopolymers, and proteins. The model systems were irradiated at 0, 2.5, 5, or 10 kGy using a linear accelerator and the amounts of CO, CO 2, and CH4 produced were dete...

In the field of biomolecular simulations, dynamics of phospholipid membranes is of special interest. A number of proteins, including channels, transporters, receptors and short peptides are embedded in lipid bilayers and tightly interact with phospholipids. While the experimental measurements report on the spatial and/or temporal average membrane properties, simulation results are not restricte...

Polar lipids are important membrane components of plant cells. They are known to affect certain membrane properties like permeability, fluidity and active transport. In the present study, individual leaf buds were tagged on the day of appearance and sampling began 7 days later. Additional samples were taken at 7 days intervals until leaf abscission occurred about 77 days after tagging. The expe...

approved: Elisabeth S..'Yearick A study was made of the effects of lecithin supplementation in order to assess possible changes in plasma factors related to atherosclerosis. Subjects were 30 middle-aged males, mean age 49; the group was fairly sedentary, but had low blood cholesterol (mean, 202 mg/dl), and was on the average only 5% above their desirable weight for height. Their recorded, free-...

Using cytochrome oxidase and esterase assays as a guide, mitochondria and microsomes were prepared from ox heart homogenate with about 25% cross-contamination of phospholipid. By the same criteria, the lipid complement of well washed myofibrils was essentially microsomal in origin. Approximately 60% of the phospholipid of the whole homogenate was found to be associated with microsomes, about ha...