نتایج جستجو برای: phosphoprotein
تعداد نتایج: 4750 فیلتر نتایج به سال:
In a previous communication (Li, H.-C., Hsiao, K.-J., and Chan, W. W. S. (1978) Eur. J. Biochem 84,215-225) we reported the purification of a divalent cation-independent, nonspecific phosphoprotein phosphatase (phosphatase S, M, = 35,000) from canine cardiac muscle to apparent homogeneity. It was found that the homogeneous enzyme preparation exhibited significant activity toward p-nitrophenyl p...
The appearance of phosphoprotein in the plasma of male birds treated with estrogen has been reported by other investigators (1, 2). Earlier studies from this laboratory have indicated that this process reflects synthesis de novo of a protein fraction normally absent in cockerels and that the initial action of the hormone requires an intact ribonucleic acid-synthesizing system (3). In the presen...
In a previous communication (Heald, 1957 b) it was shown that the 'phosphoprotein' fraction of cerebral tissues was implicated in the rapid phosphateexchange reactions promoted by applied electrical pulses (Heald, 1956b). It was pointed out that owing to the crudeness of the analytical methods employed the nature of the phosphoprotein could not be determined, more especially since its estimatio...
Posttranslational modification of target substrates underlies biological processes through activation/inactivation of signaling cascades. To concurrently identify the phosphoprotein substrates associated with cardiac beta-adrenergic signaling, the mouse myocyte phosphoproteome was analyzed using 2-D gel electrophoresis in combination with 32P autoradiography. Phosphoprotein spots, detected by s...
BACKGROUND: Newcastle disease virus (NDV) is the causativeagent of the Newcastle disease (ND), a highly contagiousdisease in birds that causes significant economic losses to thepoultry industry worldwide. ND is endemic in Iran and outbreaksare reported regularly in commercial poultry flocks and differentspecies of birds. OBJECTIVES:The current study was carried outto characterize NDV based on p...
ARPP-16, ARPP-19, and ENSA are inhibitors of protein phosphatase PP2A. ARPP-19 and ENSA phosphorylated by Greatwall kinase inhibit PP2A during mitosis. ARPP-16 is expressed in striatal neurons where basal phosphorylation by MAST3 kinase inhibits PP2A and regulates key components of striatal signaling. The ARPP-16/19 proteins were discovered as substrates for PKA, but the function of PKA phospho...
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