computational tools are reliable alternatives to laborious work in chimeric protein design. in this study, a chimeric antigen was designed using computational techniques for simultaneous detection of anti-htlv-i and anti-hbv in infected sera. databases were searched for amino acid sequences of hbv/hlv-i diagnostic antigens. the immunodominant fragments were selected based on propensity scales. ...

how to cite this article: ordooei m, mottaghipisheh h, fallah r, rabiee a. cognitive outcomes for congenital hypothyroid and healthy children: a comparative study. iran j child neurol. 2014 autumn;8(4): 28-32. abstract objective early diagnosis and treatment of congenital hypothyroidism (ch) and the prevention of developmental retardation is the main goal of public health national screening pro...

the diabetes is an autoimmune disease, in which the role of autoantibodies is of a specific importance. the appearance of these autoantibodies can be the first symptom in the serum of type i diabetic patients, which may appear ten years before onset of the disease. the most important autoantibodies include glutamic acid decarboxylase autoantibodies (gad65-ab). this can be used as a good tool fo...

background: malaria is the most important transfusion-transmitted infection (tti) in worldwide after viral hepatitis and human immunodeficiency virus (hiv) infection. the main objective of the present study was to review and evaluate the transmission of malaria via blood transfusion in iran. methods : a literature search was done without time limitation in the electronic databases as follows: p...

using enrichment procedures, 45 organic solvent-tolerant lipase producer bacterial strains were screened from areas contaminated by oil and organic solvents. among the strains, 15 isolates exhibited extreme stability toward organic solvents and high lipolytic activity. the neb-1 isolate which was later identified as   pseudomonas sp. strain neb-1 by biochemical tests and 16s rdna gene sequ...

background and objective: the aim of this study was to compare the screening performance of a new modified liquid-based cytology method (liquiprep™) with conventional pap smear (cp) in a low risk population, using colposcopy followed by histology as “gold standard”. patients and methods:  this cross-sectional study was performed on random referred specimens to a general gynecological clinic in ...

background & objectives: cancer is a serious problem for human being and is becoming a serious problem day-by-day .a prerequisite for any therapeutic modality is early diagnosis. automated cancer diagnosis by automatic image feature extraction procedures can be used as a feature extraction in the field of fractal dimension. the aim of this survey was to introduce a quantitative and objectiv...

background: type ii diabetes is known as one of the most important, prevalent, and expensive diseases of mankind. late diagnosis and subsequent delayed initiation of treatment or surveillance of patients create a variety of problems for affected individuals. this has raised increasing concerns for public health authorities throughout the world. in the current study, we aimed to find a new appro...

hepatitis b virus (hbv) infection is the most common cause of end stage liver disease in iran and in golestan province. large-scale population-based prospective cohort studies with long term follow-up are the method of choice to accurately understand the natural course of hbv infection. to date, several studies of hbv epidemiology, natural history, progression to cirrhosis and association with ...

in hungary, ecg is a keystone of routine athletic screening. its significance is based on simplicity, quickness and high informative value as well as the fact that appearance of pathological ecg signs can precede the formation of structural heart diseases. during screening of healthy athletes, we studied the incidence of athletic ecg changes and pathological ecg abnormalities. methods: we pe...