Picogram quantities of norepinephrine were found in cochlear regions of pigmented and non-pigmented rats. These regions of the cochlea were the modiolus, organ of Corti--osseous spiral lamina and the lateral cochlear wall. The content of norepinephrine in the modiolus and lateral cochlear wall of the pigmented rat was significantly greater than that in areas of the non-pigmented rat. In contras...

a hypertrophic scar is defined as an excess healing response that is a dilemma for physicians. several therapies are available: intralesional corticosteroids, topical treatments, cryotherapy, surgery, radiation, silicone gel dressing and laser therapy.pulsed-dye, nd-yag and co2 lasers have been used for treatment of keloids and hypertrophic scars but recurrence is common. recently low-level las...

Melanin is thought to serve in photoprotection. To investigate this, we have compared the responses of cultured human melanocytes derived from different pigmentary phenotypes (skin types I-VI) to a single irra diation with different doses of I A li light, ranging between 11.7 and 70.1 m.l/rm'. After I \ I! irradiation, heavily pigmented melanocytes had the same percent survival but a greater ca...

OBJECTIVES To describe the relevant morphologic features and to create a simple diagnostic method for pigmented basal cell carcinoma (BCC) using in vivo cutaneous surface microscopy (ie, dermoscopy, dermatoscopy, or oil epiluminescence microscopy). DESIGN Pigmented skin lesions were photographed in vivo using immersion oil (surface microscopy). All pigmented skin lesions were excised and revi...

Staphyloxanthin (STX), a golden carotenoid pigment produced by Staphylococcus aureus, is suggested to act as an important virulence factor due to its antioxidant properties. Restraining biosynthesis of STX was considered as an indicator of virulence decline in pigmented S. aureus isolates. However, it is not clear whether natural nonpigmented S. aureus isolates have less virulence than pigmente...

Neurofibromas are benign peripheral nerve sheath tumors seen arising both sporadically and in patients with neurofibromatosis syndromes. Commonly they of three types: localized, diffuse or plexiform. Pigmented neurofibromas very rare, accounting to <1% all reported. We present a case 64 year old woman Neurofibromatosis 1, large swelling on the right thigh. The mass was grossly pigmented micr...

Pigmented Bowens disease is an in situ squamous cell carcinoma, which is seldom reported in white patients. Herein we report a 20-year-old woman with type III skin, who had this lesion on the fourth finger of her right hand, similar to superficial malignant melanoma, clinically. Although dermoscopic evaluation could be helpful, correct diagnosis of non-melanotic origin is done by histological e...