Abstract Background: Distal Radial fracture is one of the most common fractures of the skeletal system. Although it has been believed to be a simple fracture with excellent outcomes, practical operations’ results have always been undesirable and even poor. The goal of this study was to compare two methods of treatment “pin and plaster and precautious pin fixation in patients with unstable extr...

1 Associate Professor, Department of Medicine, Government Medical College-Haldwani, District Nainital, PIN 263139, Uttarakhand, India 2 Assistant Professor, Department of Radiotherapy, Government Medical College-Haldwani, District Nainital, PIN 263139, Uttarakhand, India 3 Associate Professor, Department of Radiotherapy, Government Medical College-Haldwani,District Nainital, PIN 263139, Uttarak...

A common mode of limb suspension for transtibial amputees is the pin liner/shuttle lock system. Despite its popularity, some clinicians question its use because of observed daily and chronic changes to the residual limb. For this study, we measured limb interface pressures during ambulation with pin and suction suspension systems. No pressure differences were seen between the modes of suspensio...

OBJECTIVE To develop a distance measure based methodology to support the morphological evaluation of high grade prostatic intraepithelial neoplasia (PIN), a direct precursor of prostate cancer. METHODS Eight morphological and cellular features were analysed in 20 cases of high grade PIN found in radical prostatectomy specimens from patients with adenocarcinoma. The diagnostic distance was eva...

PURPOSE To review the infection rate in 43 patients who underwent percutaneous Kirschner wire fixation for distal radius fractures. METHODS Records of 13 men and 30 women aged 25 to 86 (mean, 49) years who underwent closed reduction and percutaneous Kirschner wire fixation for unstable distal radius fractures were reviewed. Each fracture was fixed with 2 to 3 wires of 1.6-mm diameter. Kirschn...

Dear Editor These ultrasound images (Fig. 1. Images A–D) convey an enlarged posterior interosseous nerve (PIN) with interruption of the PIN course by dislodgement of the distal of two Mitek anchors inserted 5 years previously for a biceps tendon rupture raising suspicion of PIN transection at the level of the distal biceps anchor. Surgical exploration confirmed complete PIN laceration with the ...

Impaired Ca2+ signaling in prostate cancer contributes to several cancer hallmarks, such as enhanced proliferation and migration and a decreased ability to induce apoptosis. Na+ influx via transient receptor potential melastatin 4 channel (TRPM4) can reduce store-operated Ca2+ entry (SOCE) by decreasing the driving force for Ca2+. In patients with prostate cancer, gene expression of TRPM4 is el...

conclusions in treatment of intra-articular distal radius fractures in middle-aged patients internal fixation with locking plates may be prefered to pin and plaster as the treatment of choice. results sf-36 test demonstrated a better general health (p < 0.001), mental health (p = 0.006), physical functioning (p < 0.001), social functioning (p < 0.001) and energy/fatigue (p < 0.001) in lcp group...

High grade prostatic intraepithelial neoplasia (PIN) is the most likely precursor of prostatic carcinoma. PIN has a high predictive value as a marker for carcinoma, and its identification in biopsy specimens warrants repeat biopsy for concurrent or subsequent carcinoma. The only methods of detection are biopsy and transurethral resection; PIN does not greatly raise the concentration of serum pr...