Chronic administration of aged garlic extract has been shown to prevent memory impairment in mice. Acute and chronic (21 days) effects of marketed formulation of crude garlic extract (Lasuna) were evaluated on learning and memory in mice using step down latency (SDL) by passive avoidance response and transfer latency (TL) using elevated plus maze. Scopolamine (0.4 mg/kg, ip) was used to induce ...

The aim of this analysis was to assess antidepressant & nootropic capacity Bougainvillea Glabra aqueous extract (BGAE). Forced swim test, tail suspension tetrabenazine mediated catalepsy ptosis models were used BGAE's efficacy in mice at doses 250 500 mg/kg orally. Morris water maze with elevated plus (EPM) test behaviour. Normal medications for function imipramine (25 mg/kg) piracetam (300...

A method to predict crystal structures of crystaline drugs by systematic searching for minimum-energy packings is outlined. It bases on the use of the observed space-group occurrence factors to postulate crystal symmetry. The search region is chosen within the fundamental unit of multi-dimensional crystal-structure parameter space, including the cell parameters and rigidbody mlecular parameters...

Breath holding spells are a common and dramatic form of syncope and anoxic seizure in infancy. They are usually triggered by an emotional stimuli or minor trauma. Based on the color change, they are classified into 3 types, cyanotic, pallid, and mixed. Pallid breath holding spells result from exaggerated, vagally-mediated cardiac inhibition, whereas the more common, cyanotic breathholding spell...