— Thanks to the emergence of the Personalized Information System (PIS), it becomes possible to supply the user only with the pertinent information that directly interests him/her and suits his/her preferences. However, we need beforehand to evaluate these systems in real situations. In this paper, we point out the insufficiencies in the evaluation of the PIS. Then, we propose a new evaluation m...

Typical bimolecular photoinitiators (PIs) for radical polymerization of acrylates show only poor photoreactivity because of the undesired effect of back electron transfer. To overcome this limitation, PIs consisting of a benzaldoxime ester and various sensitizers based on aromatic ketones were introduced. The core of the photoinduced reactivity was established by laser flash photolysis, photo-C...

Background: Antiretroviral therapy has increasingly improved management of HIV infection, ensuring long-term efficacy and tolerability. Each class antiretrovirals has, however, different characteristics tolerability profiles. The literature data show that protease inhibitors (PIs) are associated with a higher incidence dyslipidemia. aim our study was to evaluate whether patients treated PIs hav...

We have completed a multi-year study of ecosystem carbon fluxes across Amazônia using the Simple Biosphere model (SiB2) at several spatial and temporal scales. We have developed understanding and confidence in the model simulations at local scales by direct evaluation against data collected in the field, and extrapolated to regional, Basin, and even global scales by coupling our local ecophysio...

Conformal inference is a popular tool for constructing prediction intervals (PIs). Due to the consideration of computational burden, one most commonly used conformal methods split conformal, which generally suffers from introducing extra randomness and reducing effectiveness training models. A natural remedy use multiple splits; however, it still challenging obtain valid PIs because dependence ...

Using thin-layer agarose gel isoelectric focusing overlaid with thin-layer erythrocyte agar plates, we found that crude streptolysin O (SLO) consisted of a variety of hemolytic components with different isoelectric points (pIs) and that the distribution of pIs in crude SLO was different even in samples which were produced from a single strain of Streptococcus pyogenes under similar conditions. ...

Human immunodeficiency virus (HIV) protease inhibitors (PIs) have been used successfully in extending the life span of people infected with HIV. The use of PIs has also been associated with dyslipidemia and an increased risk of cardiovascular disease, but the underlying mechanisms remain elusive. Several PIs have been implicated in activating the nuclear receptor pregnane X receptor (PXR), whic...

Methods Inf Med 2015; 54: 379–381 http://dx.doi.org/10.3414/ME15-04-0003 received: March 6, 2015 accepted: May 29, 2015 epub ahead of print: June 25, 2015 * Supplementary online material published on our website www.methods-online.com Dear Editor, The main aim of this brief communication was to highlight how automatic methodologies are useful in the process of optimization of medicinal package ...

PURPOSE Previous research has demonstrated the fluency-improving effect of reducing the occurrence of short-duration, phonated intervals (PIs; approximately 30-150 ms) in individuals who stutter, prompting the hypothesis that PIs in these individuals' speech are not distributed normally, particularly in the short PI ranges. It has also been hypothesized that this nonnormal PI distribution will ...