AIM To determine whether circular RNAs (circRNAs) are involved in pathological processes of gastric cancer (GC). METHODS Three circRNAs with differential expression in GC and colorectal cancer were randomly selected for validation by quantitative reverse transcription-polymerase chain reaction (qRT-PCR), using 20 pairs of gastric tissues and normal tissues. Based on the predicted circRNA-miRN...

BACKGROUND The diagnostic and prognostic values of plasma B-type natriuretic peptide (BNP) testing are established. However, the range of plasma BNP levels present in the setting of chronic, stable systolic heart failure (HF) is unclear. METHODS AND RESULTS We followed up 558 consecutive ambulatory patients with chronic, stable systolic HF (left ventricular ejection fraction <50%) treated at ...

Background: The aim of this study was to investigate the association between plasma levels of homocysteine and the occurrence and progression of rectal cancer. Material/Methods: The 320 study participants included healthy controls (n=80). and patients with rectal tumors (n=240), including 155 patients with rectal cancer, Stage I (n=32), Stage II (n=38), Stage III (n=50), and Stage IV (n=35), an...

Fifteen patients with hypertension due to phaeochromocytoma and 35 controls with essential hypertension were studied to assess the diagnostic value of urinary and plasma biochemical determinations in phaeochromocytoma. In every case of phaeochromocytoma the urinary concentration of vanillylmandelate, metanephrines, or adrenaline plus noradrenaline was diagnostic of the disease irrespective of w...

An upgraded spectral motional Stark effect diagnostic has been installed on the gas-dynamic trap (GDT) experiment to enable spatially resolved measurement of |B|. A new low-noise charge-coupled device detector, combined with enhancements of the diagnostic neutral beam, allows single-shot profile measurements. Previously only single-point motional Stark effect measurements were possible, and det...

In this Letter we report measurements of collective Thomson scattering (CTS) spectra with clear signatures of ion Bernstein waves and ion cyclotron motion in tokamak plasmas. The measured spectra are in accordance with theoretical predictions and show clear sensitivity to variation in the density ratio of the main ion species in the plasma. Measurements with this novel diagnostic demonstrate th...

Background RNA detection in plasma/stool is the gold-standard for diagnosis of hepatitis E virus (HEV) infection. The impact viral extraction methods on HEV poorly investigated. Methods We determined limit RealStar RT-PCR V2.0 Kit (altona Diagnostics, RS) utilizing 3 (COBAS® AmpliPrep Total Nucleic Acid Isolation Kit, TNAi Roche; MagNA Pure 96 DNA, Viral NA SV MgP; QIAamp mini Qiagen; VRK) plas...

Active Plasma Resonance Spectroscopy (APRS) is a well-established plasma diagnostic method: radio frequency signal coupled into the via probe or antenna, excites it to oscillate, and response evaluated through mathematical model. The majority of APRS probes are invasive perturb by their physical presence. planar multipole resonance (pMRP) solves this problem: can be integrated chamber wall mini...

The lithium beam diagnostic at COMPASS is designed for measurements of the edge plasma density profile and fluctuations and edge plasma current fluctuations. The principle of the diagnostic is detection of light coming from collisionally excited Li atoms — beam emission spectroscopy (BES) and a direct detection of the ionized part of the beam (atomic beam probe — ABP). For slow density measurem...

Much research interest has been shown in recent years for the development of molecular diagnostic strategies based on the analysis of DNA/RNA molecules that are present in the plasma/serum of human subjects. Reported applications include the diagnosis, prognostication or monitoring of malignancies and pregnancy-associated complications. While researchers have speculated that cell death is a pot...