نتایج جستجو برای: platelet derived growth factor

تعداد نتایج: 1930780  

Journal: :American journal of respiratory cell and molecular biology 2006
Ynuk Bossé Charles Thompson Jana Stankova Marek Rola-Pleszczynski

Bronchial smooth muscle cell (BSMC) hyperplasia is a typical feature of airway remodeling and contributes to airway obstruction and hyperresponsiveness in asthma. Fibroblast growth factor 2 (FGF-2) and transforming growth factor beta1 (TGF-beta1) are sequentially upregulated in asthmatic airways after allergic challenge. Whereas FGF-2 induces BSMC proliferation, the mitogenic effect of TGF-beta...

Journal: :Cancer research 2007
Gudrun Reiterer Andrew Yen

Here, we show that the platelet-derived growth factor receptor (PDGFR) regulates myeloid and monocytic differentiation of HL-60 myeloblastic leukemia cells in response to retinoic acid (RA) and vitamin D3 (D3), respectively. Both RA and D3 decreased the expression of PDGFR-alpha and PDGFR-beta throughout differentiation. When cells were treated with the PDGFR inhibitor AG1296 in addition to RA ...

Journal: :iranian red crescent medical journal 0
rasoul eslami faculty of physical education and sport sciences, allameh tabataba’i university, tehran, ir iran reza gharakhanlou physical education department, faculty of humanity and literature, tarbiat modares university, tehran, ir iran abdolreza kazemi neuroscience research center, institute of neuropharmacology, kerman university of medical sciences, kerman, ir iran; physical education department, faculty of humanity and literature, vali-e-asr university of rafsanjan, rafsanjan, ir iran; neuroscience research center, institute of neuropharmacology, kerman university of medical sciences, kerman, ir iran and physical education department, faculty of humanity and literature, vali-e-asr university of rafsanjan, rafsanjan, ir iran. tel: +98-9133982706 amir bahador dakhili neuroscience research center, institute of neuropharmacology, kerman university of medical sciences, kerman, ir iran ghazaleh sorkhkamanzadeh neuroscience research center, institute of neuropharmacology, kerman university of medical sciences, kerman, ir iran ayob sheikhy department of statistics, faculty of mathematics and computer, shahid bahonar university of kerman, kerman, ir iran

conclusions this study shows that bdnf and ngf expression decreases in diabetic neuropathy. however, this decrease can be reversed through endurance training. these results also indicate that endurance training may have a potential role in compensating for neurotrophin deficiency following diabetic neuropathy. objectives this experimental study was designed and carried out at the tarbiat modare...

Journal: :Proceedings of the National Academy of Sciences 1979

Journal: :Frontiers in bioscience 2014
Michael Karsy Tiangui Huang George Kleinman Georg Karpel-Massler

Glioblastoma (GBM), the most common primary brain tumor, has a poor median prognosis despite modern surgical, chemotherapeutic, and radiation modalities, which have shown little clinical efficacy. Initially categorized by clinicopathological classification into de novo primary GBM and secondary GBM, which arises from lower-grade glioma, genomic studies have elucidated several distinct genotypes...

2013
Qiong Wu Rui Wang Qingling Yang Xin Hou Sulian Chen Yueyue Hou Changjie Chen Yan Yang Lucio Miele Fazlul H Sarkar Yuqing Chen Zhiwei Wang

Hepatocellular carcinoma (HCC) is one of the common malignances in the world and has high mortality in part due to development of acquired drug resistance. Therefore, it is urgent to investigate the molecular mechanism of drug resistance in HCC. To explore the underlying mechanism of drug resistance in HCC, we developed gemcitabine-resistant (GR) HCC cells. We used multiple methods to achieve o...

2013
Christina L. Papke Jiumei Cao Callie S. Kwartler Carlos Villamizar Katerina L. Byanova Soon-Mi Lim Harini Sreenivasappa Grant Fischer John Pham Meredith Rees Miranda Wang Christine Chaponnier Giulio Gabbiani Aarif Y. Khakoo Joya Chandra Andreea Trache Warren Zimmer Dianna M. Milewicz

muscle a-actin is driven by activation of focal adhesion kinase, altered p53 localization and increased levels of platelet-derived growth factor receptor-b Christina L. Papke1,, Jiumei Cao1,,, Callie S. Kwartler1,, Carlos Villamizar1, Katerina L. Byanova1, Soon-Mi Lim2, Harini Sreenivasappa2,3, Grant Fischer1, John Pham1, Meredith Rees1, Miranda Wang1, Christine Chaponnier4, Giulio Gabbiani4, A...

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