Abstract Background In continuous renal replacement therapy (CRRT), administration of anticoagulants is necessary for achieving a certain level filter lifetime. Generally, anticoagulant doses are controlled to keep activated partial thromboplastin time and other indicators within target range, regardless the membrane materials used filter. However, in actual clinical practice, lifetime varies s...

Polymethylmethacrylate (PMMA) has been widely used as transparency in aerospace and automobile engineering to enhance structural reliability under impact loading such bird strike events. This study investigates the confined compressive behaviour of PMMA at quasi-static 0.01 s−1, medium rate 1-100 s−1 intermediate strain rates 100-1000 from room temperature elevated temperatures. Constant is ach...

BACKGROUND Infection due to methicillin-resistant Staphylococcus aureus (MRSA) is increasingly common in nosocomial and community settings. Daptomycin is a cyclic lipopeptide anti-infective with activity against MRSA, approved for treatment of complicated skin and skin structure infections. Daptomycin may be useful in systemic or local treatment of chronic osteomyelitis. METHODS We measured m...

Polymethylmethacrylate (PMMA) bone cement is a popular bone void filler for vertebroplasty. However, the use of PMMA has some drawbacks, including the material's excessive stiffness, exothermic polymerization, and short handling time. This study aimed to create an ideal modified bone cement to solve the above-mentioned problems. Modified bone cements were prepared by combining PMMA with three d...

Osteoporosis causes a decrease in bone mineral density. To overcome the decrease in fixation strength, a variety of techniques and devices have been developed, including cement augmentation of pedicle screws. Polymethyl methacrylate (PMMA), is commonly known as bone cement, and is widely used for implant fixation in various orthopaedic and spine surgery. In general, PMMA augmentation of pedicle...

Gentamicin (G) and vancomycin (V) concentrations in drainage fluids obtained from patients during the first 24 hours after implantation of antibiotic-loaded polymethylmethacrylate (PMMA) spacers in two-stage revision of infected total hip arthroplasty were studied. The inhibitory activity of drainage fluids against different multiresistant clinical isolates was investigated as well. Seven hips ...

Optical microscopy and multi-particle tracking are used to study hydrodynamic interactions of monodisperse polymethylmethacrylate (PMMA) spheres at a decalin– water interface. The short-time self-diffusion coefficient measured at low surface coverage has the form D S (n)=αD0(1−βn), where n is the area fraction occupied by the particles, and D0 is the Stokes–Einstein diffusion coefficient in the...

Bioactive bone cement (BABC) is a novel artificial bone cement. It has some noteworthy characteristics that are applicable to neurological surgery. The toxicity of BABC to the nervous system was tested by implanting BABC and polymethylmethacrylate (PMMA) cement as a control at the parietal and the suboccipital regions of the skull in beagles. The auditory brainstem response (ABR) was tested bef...

ArteFill is a novel, third-generation polymethylmethacrylate (PMMA) injectable filler with unique properties. When compared with predecessor materials, ArteFill demonstrates improved biocompatibility as a result of more uniform PMMA microsphere size and shape. This translates into less adverse events after placement. ArteFill can provide a permanent volume enhancement by stimulation of fibrobla...