Internal plasticization of poly(vinyl chloride) (PVC) was achieved in one-step using copper-mediated atom transfer radical polymerization to graft different ratios random n-butyl acrylate and 2–2-(2-ethoxyethoxy)ethyl copolymers from defect sites on the PVC chain. Five polymers were made with poly(butyl acrylate) (PBA) poly(2–2-(2-ethoxyethoxy)ethyl (P2EEA); glass transition temperatures (Tg) f...

The GLD-2 family of poly(A) polymerases add successive AMP monomers to the 3' end of specific RNAs, forming a poly(A) tail. Here, we identify a new group of GLD-2-related nucleotidyl transferases from Arabidopsis, Schizosaccharomyces pombe, Caenorhabditis elegans, and humans. Like GLD-2, these enzymes are template independent and add nucleotides to the 3' end of an RNA substrate. However, these...

The paper reports a facile synthesis of novel anionic spherical polymer brushes which was based on grafting sodium 2-acrylamido-2-methylpropane-1-sulfonate from the surface 4,4′-Azobis (4-cyanopentanoyl chloride)-modified carbon spheres. Various characterization methods involving scanning electron microscope, energy dispersive X-ray spectroscopy, Fourier transform infrared spectrum, and thermo-...

in this work, new biodegradable abcba type pentablock copolymers with different mole ratio of l-lactide and ppdo-b-peg-b-ppdo triblock copolymer were synthesized and characterized. in the first step, ppdo-b-peg-b-ppdo triblock copolymer was synthesized via a ring-opening polymerization of p-dioxanone (pdo) monomer with poly (ethylene glycol) (peg) using stannous octoate (sn(oct)2) as the cataly...

Triple helix formation of oligodeoxynucleotides (ODNs) with a 15 base pair poly-purine DNA target in the HER2 promoter was examined by footprinting analysis. 7-deaza-2'-deoxyxanthosine (dzaX) was identified as a purine analogue of thymidine (T) which forms dzaX:A-T triplets. ODNs containing 2'-deoxyguanosine (G) and dzaX were found to form triple helices in an anti-parallel orientation, with re...

Recognition of nucleic acids is important for our understanding of nucleic acid structure as well as for our understanding of nucleic acid-protein interactions. In addition to the direct readout mechanisms of nucleic acids such as H-bonding, shape recognition of nucleic acids is being increasingly recognized as playing an equally important role in DNA recognition. Competition dialysis, UV, flou...