The organic single crystals of 4-nitroaniline 4aminobenzoic acid (4NAABA) were grown from ethanol solvent. The grown crystals have been confirmed from single crystal XRD analysis. The UV absorption was carried out which shows the cutoff wavelength around 459 nm. The optical band gap of the crystal has been evaluated from the absorption spectra and absorption coefficient by extrapolation techniq...

The occurrence of many of the water-soluble vitamins in sweat has been reported in recent years. Sargent, Robinson, and Johnson (1) have reviewed the literature on the occurrence of ascorbic acid, dehydroascorbic acid, thiamine, riboflavin, pantothenic acid, and nicotinic acid in sweat. We have demonstrated the presence of pyridoxine and its metabolites (2), choline (3), N1-methylnicotinamide (...

1. Chronic renal failure was induced in rats by surgical removal of thirteen-sixteenths of renal tissue. 2. The metabolism of p-amino[14C]benzoic acid was studied in the isolated perfused livers of control and chronically uraemic rats. There was a slower rate of clearance and decreased overall metabolism of the compounds in the uraemic rats. 3. Conjugation of p-amino[14C]benzoic acid with glyci...

Although the postulate that p-aminobenzoic acid (PABA) functions as a precursor of a folic acid-like compound in the metabolism of microorganisms is widely accepted, there is little or no information on the possible intermediates which may be involved in this pathway of synthesis. There still may be some question as to the exact nature of the active end product but the more recent data concerne...

We describe a new approach to the bentiromide test of exocrine pancreatic function, p-Aminosalicylic acid (PAS), a compound closely related to the bentiromide fragment p-aminobenzoic acid (PABA), is used as a marker of the pharmacokinetic behavior of PABA to derive a PABA excretion index. This index is identical to that derived with [14C]-PABA. Concentrations of both PABA and PAS are measured i...

Phorbol ester-induced promotion of initiated NMRI mouse skin keratinocytes to papillomas could be largely prevented when nicotinamide-like inhibitors of poly(ADP-ribose)polymerase (nicotinamide, benzamide, 3-aminobenzamide) were applied simultaneously with 12-O-tetradecanoylphorbol-13-acetate (TPA). A similar suppression of tumor promotion by nicotinamide analogues was demonstrated in clone 41 ...

In the structure of the title compound, C(10)H(10)N(2) (2+)·2ClO(4) (-)·4C(7)H(7)NO(2)·2C(10)H(8)N(2)·2H(2)O, the 4,4'-bipyridinium cation has a crystallographically imposed centre of symmetry. The cation is linked by N-H⋯N hydrogen bonds to adjacent 4,4'-bipyridine mol-ecules, which in turn inter-act via O-H⋯N hydrogen bonds with 4-amino-benzoic acid mol-ecules, forming chains running parallel...