background: polycystic ovary syndrome (pcos) is a complex, multifaceted, heterogeneous disorder, affecting 4%-18% of reproductive-aged women and it is associated with reproductive, metabolic and psychological dysfunctions. pcos affects quality of life and can worsen anxiety and depression either due to the features of pcos or due to the diagnosis of a chronic disease. methods: in this descripti...

for the present study, and follow-up of histochemical changes in estradiol valerate-induced polycysticovary syndrome (pcos), 48 virgin 90-day-old female rats were used. the rats were divided into thetreatment and control groups. for each rat of the treatment group, 4 mg estradiol valerate was injectedthrough intramuscular route for the induction of pcos. the control group was taken the same amo...

background: polycystic ovarian syndrome (pcos) has been shown to cause a reduction in health-related quality of life (hrqol). objective:  this study examines the extent of different clinical symptoms in pcos patients on hrqol. materials and methods:  a cross-sectional study was undertaken to ascertain the factors related to hrqol in 200 pcos patients in kashan, iran. main outcome measures were ...

1 Elif Karadeli1, Ayla Uckuyu2, Faika Ceylan Ciftci2, Erzat Toprak2, Erdem Turhan2, Emel Ozcimen2, Emin Alp Niron1 1Department of Radiology, 2Department of Obstetrics and Gynecology, Baskent University, Faculty of Medicine, Turkey Renal Doppler Ultrasonografi, Polikistik Over Sendromu / Renal Doppler Ultrasound, Polycystic Ovary Syndrome Polycystic Ovary Syndrome: The Correlation Between Renal ...

A 65 year old patient with polycystic liver disease presented with obstructive jaundice thought to be a cholangiocarcinoma. Subsequent investigations demonstrated a large cyst compressing the confluence of the hepatic ducts. Percutaneous decompression of the biliary tree led to a complication necessitating surgery. Treatment options for symptomatic polycystic liver disease are reviewed.

BACKGROUND AND OBJECTIVES Plasma copeptin, a marker of arginine vasopressin, is elevated in patients with autosomal dominant polycystic kidney disease and predicts disease progression. It is unknown whether elevated copeptin levels result from decreased kidney clearance or as compensation for impaired concentrating capacity. Data from patients with autosomal dominant polycystic kidney disease a...

BACKGROUND The Canadian and American Diabetes Associations recommend the use of an oral glucose tolerance test to screen for abnormal glucose tolerance among women with polycystic ovary syndrome when their fasting plasma glucose level is 5.7 mmol/L or more (Canadian guideline) and 5.6 mmol/L or more (American). Our objective was to determine the predictive value of 5.6 mmol/L as a fasting plasm...

In 1935 Stein and Leventhal described seven hirsute and infertile women with amenorrhoea or oligomenorrhoea in whom bilateral cystic ovarian enlargement was found at laparotomy' and thereby gave their names to a polycystic ovarian disorder. Since then, however, the protean manner of clinical presentation and the variability of biochemical changes in patients with this condition have led some pe...

G protein-coupled receptor 48 (Gpr48/Lgr4) is essential to regulate the development of multiple tissues in mice. The notion that Gpr48 functions in renal development prompted us to investigate the relation between Gpr48 and renal diseases. Using a Gpr48 knockout mice model, we observed that 66.7% Gpr48 null mice developed polycystic lesions in the kidney, while no cysts were observed in the kid...

Polycystic livers are seen in the rare inherited disorder isolated polycystic liver disease (PCLD) and are recognized as the most common extrarenal manifestation in autosomal dominant polycystic kidney disease. Hepatic cystogenesis is characterized by progressive proliferation of cholangiocytes, ultimately causing hepatomegaly. Genetically, polycystic liver disease is a heterogeneous disorder w...