Functionalized carbohydrate-centered glycoclusters formed the starting material for the synthesis of tagged oligosaccharide and glycoconjugate mimetics, which were obtained by thiourea-bridging, peptide coupling and in particular squaric diester-mediated coupling. The latter method could also be utilized to provide new multivalent glycoconjugates, which were tested for their anti-adhesive prope...

Creating efficient artificial catalysts that can compete with biocatalysis has been an enduring challenge which has yet to be met. Reported herein is the synthesis and characterization of a series of zinc complexes designed to catalyze the hydrolysis of phosphate diesters. By introducing a hydrated aldehyde into the ligand we achieve turnover for DNA-like substrates which, combined with ligand ...

In the title compound, C(32)H(40)N(4)O(4), the pyrrole rings and ester groups adopt a 1,3-alternate conformation in which the alternating pyrrole and ester units are in opposite directions. The structure displays N-H⋯O hydrogen bonding and exhibits disorder [site occupancies of 0.81(2) and 0.71(2)] in the peripheral ethyl groups.

Biobased monomers derived from castor oil as well as from limonene suitable for thiol–ene copolymerization were synthesized. Di‐10‐undecenylether 2 was obtained via GaBr3‐catalyzed reduction of 10‐undecenyl 10‐undecenoate 1. Diene ether 2 and (R)‐limonene 5 were reacted in two steps using radical thiol–ene addition reactions to dithiol ether 4 and dithiol 7, respectively. Diene ether 2 and dith...

BACKGROUND This study was carried out to evaluate the effect of two commercially available chemical disinfectants namely sodium hypochlorite and glutaraldehyde and a surface wetting agent on the wettability of three high precision elastomeric impression materials, addition silicone, condensation silicone and polyether. MATERIALS AND METHODS Three different types of elastomeric impression mate...

Interest in polyether antibiotics has remained at a high level for over 20 years, owing largely to the commercial importance of this class of drugs in veterinary medicine. For example, monensin1*, lasalocid1} and salmomycin2) are marketed as anticoccidial agents for poultry, and are used as growth permittants in cattle or swine. Narasin1} and maduramicin3) are also used as anticoccidial agents....

Introduction: Polyurethanes (PU) have long been used for biomedical applications due to their excellent mechanical properties and reasonable biocompatibility. However, polyether urethane elastomers are susceptible to biodegradation. Silicones are known to be biostable and biocompatible, making them an ideal replacement for the polyether soft segment of polyurethanes. As a result, a new silicone...

Polyurethane films have potential applications in medicine, especially for packaging implantable medical devices. Although polyether-urethanes have superior mechanical properties and are biocompatible, achieving water resistance is still a challenge. Polyether based polyurethanes with two different molecular weights (PTMO1000, PTMO2000) were prepared from 4,4’-diphenylmethane diisocyanate and p...

Mechanical properties of thermoplastic polyurethane elastomers based on either polyether or polycarbonate (PC)-glycols, 4,4'-dipheylmethane diisocyanate (1,1'-methylenebis(4-isocyanatobenzene)), 1,4-butanediol, were controlled by restriction of crystallization of polymer glycols. For the polyether glycol based-polyurethane elastomers (PUEs), poly(oxytetramethylene) glycol (PTMG), and PTMG incor...

The use of metal-organic frameworks (MOFs) so far has largely relied on nonspecific binding interactions to host small molecular guests. We used long organic struts (approximately 2 nanometers) incorporating 34- and 36-membered macrocyclic polyethers as recognition modules in the construction of several crystalline primitive cubic frameworks that engage in specific binding in a way not observed...