Plantar forefoot pain is common in older people and is related to increased peak pressures under the foot during gait. Variations in the hardness of the shoe sole may therefore influence both the magnitude of loading under the foot and the perceived comfort of the shoe in this population. The aim of this investigation was to determine the effect of varying shoe sole hardness on plantar pressure...

Rivers are viewed as major pathways of microplastic transport from terrestrial areas to marine ecosystems. However, there is paucity knowledge on the dispersal pattern and microplastics in river sediments. In this study, a three dimensional hydrodynamic particle modelling framework was created investigate processes particles commonly present environment, namely, polyethylene (PE), polypropylene...

Abstract Further innovation in the field of selective laser sintering (SLS) is strongly connected to availability new materials since market dominated by polyamide 12 (>90%). The aim this publication develop a descriptive model for droplet formation process Filament Extension Atomizer predict applicability exploit further polymers SLS process. feasibility was tested, investigated and charact...

Abstract Background The world today is faced with the humongous challenge of removing numerous plastic wastes in our environment. Efforts removal or remediation these materials from ecosystem are presently at budding stage. Some researchers have shown that certain bacterial enzymes ability to hydrolyze and further degrade compounds. In this study, PET hydrolase enzyme polyvinylchloride, polyure...

Abstract This study investigated the mechanical performance of short aramid fiber on polypropylene, polyethylene, polyamide 6, and 12. Extrusion, press molding, CNC cutting methods were used in production composite samples. Tensile, three-point bending, drop weight hardness tests composites carried out. As volume fractions increased, properties improved, but most efficient for each matrix chang...

BACKGROUND Repetitive endothelial damage from dialysis membrane incompatibility is a probable cause of accelerated atherosclerosis in haemodialysis patients. Consequently pulse wave velocity (PWV), a measure of arterial stiffness, was utilized as a surrogate marker of vascular dysfunction during dialysis with two commonly used synthetic dialysers. METHODS PWV was monitored before, during and ...

The zinc finger protein EVI1 is causally associated with acute myeloid leukemogenesis, and inhibition of its function with a small molecule therapeutic may provide effective therapy for EVI1-expressing leukemias. In this paper we describe the development of a pyrrole-imidazole polyamide to specifically block EVI1 binding to DNA. We first identify essential domains for leukemogenesis through str...