نتایج جستجو برای: polymorphic ventricular tachycardia

تعداد نتایج: 189703  

Journal: :Circulation 2014
Marco Denegri Rossana Bongianino Francesco Lodola Simona Boncompagni Verónica C De Giusti José E Avelino-Cruz Nian Liu Simone Persampieri Antonio Curcio Francesca Esposito Laura Pietrangelo Isabelle Marty Laura Villani Alejandro Moyaho Paola Baiardi Alberto Auricchio Feliciano Protasi Carlo Napolitano Silvia G Priori

BACKGROUND Catecholaminergic polymorphic ventricular tachycardia is an inherited arrhythmogenic disorder characterized by sudden cardiac death in children. Drug therapy is still insufficient to provide full protection against cardiac arrest, and the use of implantable defibrillators in the pediatric population is limited by side effects. There is therefore a need to explore the curative potenti...

Journal: :Circulation. Arrhythmia and electrophysiology 2015
Kathryn E Waddell-Smith Kjetil N Ertresvaag Jian Li Krish Chaudhuri Jackie R Crawford James K Hamill David Haydock Jonathan R Skinner

BACKGROUND Left cardiac sympathetic denervation reduces risk in long-QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia. Side effects and patient satisfaction have not been systematically analyzed in patients who underwent left cardiac sympathetic denervation. Aims of this study included documenting physical and psychological consequences and patient satisfaction after...

Journal: :British heart journal 1995
C I Noh J Y Song H S Kim J Y Choi Y S Yun

OBJECTIVE To emphasize the importance of ventricular tachycardia associated with repolarisation abnormality in syncope associated with exercise. DESIGN Retrospective analysis of data on children presenting with syncope between 1985 and 1993. PATIENTS 5 apparently normal children with recurrent exercise related syncope associated with electrocardiographically abnormal TU complexes. RESULTS...

Journal: :Circulation. Arrhythmia and electrophysiology 2015
Thomas M Roston Jeffrey M Vinocur Kathleen R Maginot Saira Mohammed Jack C Salerno Susan P Etheridge Mitchell Cohen Robert M Hamilton Andreas Pflaumer Ronald J Kanter James E Potts Martin J LaPage Kathryn K Collins Roman A Gebauer Joel D Temple Anjan S Batra Christopher Erickson Maria Miszczak-Knecht Peter Kubuš Yaniv Bar-Cohen Michal Kantoch Vincent C Thomas Gabriele Hessling Chris Anderson Ming-Lon Young Michel Cabrera Ortega Yung R Lau Christopher L Johnsrude Anne Fournier Prince J Kannankeril Shubhayan Sanatani

BACKGROUND Catecholaminergic polymorphic ventricular tachycardia is an uncommon, potentially lethal, ion channelopathy. Standard therapies have high failure rates and little is known about treatment in children. Newer options such as flecainide and left cardiac sympathetic denervation are not well validated. We sought to define treatment outcomes in children with catecholaminergic polymorphic v...

Journal: :Heart 2003
N Sumitomo K Harada M Nagashima T Yasuda Y Nakamura Y Aragaki A Saito K Kurosaki K Jouo M Koujiro S Konishi S Matsuoka T Oono S Hayakawa M Miura H Ushinohama T Shibata I Niimura

OBJECTIVE To investigate the clinical outcome, ECG characteristics, and optimal treatment of catecholaminergic polymorphic ventricular tachycardia (CPVT), a malignant and rare ventricular tachycardia. PATIENTS AND METHODS Questionnaire responses and ECGs of 29 patients with CPVT were evaluated. Mean (SD) age of onset was 10.3 (6.1) years. RESULTS The initial CPVT manifestations were syncope...

2009
Daisuke Sato Lai-Hua Xie Ali A. Sovari Diana X. Tran Norishige Morita Fagen Xie Hrayr Karagueuzian Alan Garfinkel James N. Weiss Zhilin Qu Cheng-Yu Chen Ivelin Georgiev Esterlina V. Tan Eduardo C. DeLa Cruz Randall J. Basaraba Ian M. Orme Yasir A. W. Skeiky Mark R. Alderson Karen D. Cowgill Jean-Paul Prieels Rodolfo M. Abalos Marie-Claude Dubois Joe Cohen Pascal Mettens Steven G. Reed Rhea N. Coler Wilfried Dalemans Yves Lobet Fernanda G. De Felice Marcelo N. N. Vieira Theresa R. Bomfim Helena Decker Pauline T. Velasco Mary P. Lambert Kirsten L. Viola Wei-Qin Zhao Sergio T. Ferreira

APPLIED PHYSICAL SCIENCES, MEDICAL SCIENCES Correction for ‘‘Synchronization of chaotic early afterdepolarizations in the genesis of cardiac arrhythmias,’’ by Daisuke Sato, Lai-Hua Xie, Ali A. Sovari, Diana X. Tran, Norishige Morita, Fagen Xie, Hrayr Karagueuzian, Alan Garfinkel, James N. Weiss, and Zhilin Qu, which appeared in issue 9, March 3, 2009, of Proc Natl Acad Sci USA (106:2983–2988; f...

Journal: :Cardiovascular research 2012
John S Lowe Dina Myers Stroud Tao Yang Lynn Hall Thomas C Atack Dan M Roden

AIMS Female gender is a risk factor for long QT-related arrhythmias, but the underlying mechanisms remain uncertain. Here, we tested the hypothesis that gender-dependent function of the post-depolarization 'late' sodium current (I(Na-L)) contributes. METHODS AND RESULTS Studies were conducted in mice in which the canonical cardiac sodium channel Scn5a locus was disrupted, and expression of hu...

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