Fibrous dysplasia (FD) is a relatively uncommon disorder that affects primarily the cranial region; its occurrence in the cranial base in combination with hindbrain herniation and aneurysmal bone cyst (ABC) constitutes an extremely rare condition. We report a case of polyostotic fibrous dysplasia with progressive occipital, temporal, and clival involvement. Clinical findings and differential di...

OBJECTIVES/HYPOTHESIS To characterize the spectrum, symptoms, progression, and effects of endocrine dysfunction on sinonasal disease in polyostotic fibrous dysplasia (PFD) and McCune-Albright Syndrome (MAS). STUDY DESIGN Retrospective review. METHODS A prospectively followed cohort of subjects with PFD/MAS underwent a comprehensive evaluation that included otolaryngologic and endocrine eval...

Fibrous dysplasia (FD) is a bone disorder in which fibrous tissue replaces normal bone. FD can be monostotic (10%-25%) or polyostotic (50-90%) and is typically diagnosed accidentally on radiographs. Craniofacial lesions are typically unilateral and are diagnosed by clinical assessment and radiographic evaluation. This report describes the case of a 50-yearold female patient who had presented wi...

Erdheim-Chester disease (ECD) is a rare, non-Langerhans histiocytic disorder. The most common manifestations consist of polyostotic sclerotic lesions with the majority of cases also demonstrating soft tissue involvement of the sinuses, retroperitoneum, large vessels, heart, lungs, and central nervous system. Nuclear medicine can play an important role in assessing the extent of the disease with...

Fibrous dysplasia (FD) is a condition characterized by excessive proliferation of bone forming mesenchymal cells which can affect one bone (monostotic type) or multiple bones (polyostotic type). It is predominantly noticed in adolescents and young adults. Fibrous dysplasia affecting the jaws is an uncommon condition. The most commonly affected facial bone is the maxilla, with facial asymmetry b...

FIBROUS dysplasia is a peculiar clinical entity, which is of interest to the Otolaryngologist, because at times it involves one of the paranasal sinuses. Fibrous dysplasia of the bone is the name applied by Lichtenstein (1938) to a polyostotic or monostotic condition apparently due to a perverted activity of the specific bone-forming mesenchyme. It is most frequently localized in the femur, tib...

Fibrous dysplasia is abnormal proliferation of fibrous tissue interspersed with normal or immature bone. The records of 11 cases of fibrous dysplasia of paranasal sinuses with skull base involvement were reviewed. Six patients were polyostotic and 5 were classified as monostotic fibrous dysplasia. Four cases were managed endoscopically and only 1 patient had undergone right lateral craniotomy f...