Repeat serum samples from 22 patients with proven disseminated candidiasis and 42 with simple peripheral colonization were assayed for Candida antibodies by coelectrosyneresis, immunoprecipitation, and A and B immunofluorescence, for metabolites by D-arabinitol measurement, and for antigens by the mannan immunoassay and Cand-tec latex agglutination (mean number of samples tested, 2.5 per patien...

OBJECTIVE The utility of rapid and reliable sensory tests appropriate for the diagnosis of neuropathy in the diabetes clinic, rather than as prognostic tools for the prediction of foot complications, has been unclear because of limitations inherent in previous studies. Although clinical practice guidelines recommend annual screening for neuropathy, they are unable to support specific recommenda...

BACKGROUND Enteric fever is very common infectious disease in developing countries like Nepal. Due to lack of resources diagnosis has to be clinical most of the time. Hence a proposal of clinical diagnostic criteria and validation of the same would be very useful. OBJECTIVE To validate the proposed clinical diagnostic criterion including features characterized as major and minor criteria. M...

BACKGROUND To assess the accuracy of findings from the clinical history, symptoms, signs and diagnostic tests (ECG, CXR and natriuretic peptides) in relation to the diagnosis of left ventricular systolic dysfunction (LVSD) in a primary care setting. METHODS Diagnostic accuracy systematic review, we searched Medline (1966 to March 2008), EMBASE (1988 to March 2008), Central, Cochrane and ZETOC...

AIM To evaluate if transvaginal cervical length measurement in the second-trimester scan is an effective screening test for preterm delivery. METHODS We performed a search in Medline and, for each selected article, information was extracted regarding the performance of the test in terms of sensitivity, specificity, positive, and negative likelihood ratios, in low-risk, high-risk, and multiple...

abstract background: regarding the diagnostic errors of the classic criteria including serum ascites albumin gradient (saag), total protein concentration and the adapted light et al’s criteria in distinguishing transudate versus exudates, we evaluated the ascitic fluid to serum bilirubin ratio as a new criteria in this regard. we also evaluated whether the combination of bilirubin ratio with ea...