PURPOSE Improper proliferation of lens epithelial cells is causally related to posterior capsule opacification. In the present study, we investigated whether small interfering RNA (siRNA)-mediated gene silencing of S-phase kinase-interacting protein 2 (Skp2) can be employed to inhibit rabbit lens epithelial cell (rLEC) proliferation by increasing the p27(kip1) level. METHODS A plasmid contain...

Posterior capsule opacification (PCO) remains a common complication of modern cataract surgery, although both modification of materials used and changes in the intraocular lens (IOL) optic edge design have helped to decrease its incidence slightly. Recently, various kinds of quantitative methods have been developed for measuring PCO. The purpose of this study was to compare the quantitative ana...

in a fellow-eye-controlled trial, we compared the posterior capsule opacification (pco) rates of single-piece (sa60at) and three-piece (ma60ac) hydrophobic acrylic intraocular lenses (iol) in 54 pair-matched eyes of 27 age-related cataract patients who consecutively underwent bilateral (4-8 weeks apart) phacoemulsification horizontal chopping performed through a capsulorrhexis of approximately ...

Purpose: Capsular related complications may occur during and/or following cataract s”rPew. Methods: We used endocapsular PUMA rings (EPR) to prevent such complications in eyes with pre or peroperative zonular c’ehiscence, high myopic eyes and eyes witl: exfoliation syndrome which have weak zonoles. EPR can be implanted easily through the phaco-incision before aspiration of the cortex or just be...

Purpose: Capsular related complications may occur during and/or following cataract s”rPew. Methods: We used endocapsular PUMA rings (EPR) to prevent such complications in eyes with pre or peroperative zonular c’ehiscence, high myopic eyes and eyes witl: exfoliation syndrome which have weak zonoles. EPR can be implanted easily through the phaco-incision before aspiration of the cortex or just be...

Purpose: Capsular related complications may occur during and/or following cataract s”rPew. Methods: We used endocapsular PUMA rings (EPR) to prevent such complications in eyes with pre or peroperative zonular c’ehiscence, high myopic eyes and eyes witl: exfoliation syndrome which have weak zonoles. EPR can be implanted easily through the phaco-incision before aspiration of the cortex or just be...

Purpose: Capsular related complications may occur during and/or following cataract s”rPew. Methods: We used endocapsular PUMA rings (EPR) to prevent such complications in eyes with pre or peroperative zonular c’ehiscence, high myopic eyes and eyes witl: exfoliation syndrome which have weak zonoles. EPR can be implanted easily through the phaco-incision before aspiration of the cortex or just be...

PURPOSE To compare the visual outcomes and complications of lensectomy and posterior chamber intraocular lens (PCIOL) implantation with or without posterior capsulotomy and anterior vitrectomy in older subjects with pediatric cataracts. METHODS Seventeen eyes of 12 children aged 10 to 15 years with congenital or developmental cataracts were randomly divided to two groups. Lensectomy and PCIOL...