BACKGROUND Several studies have focused on the effects of calcium intake on serum lipid concentrations in postmenopausal women. However, many premenopausal women are taking calcium supplements in China. To our knowledge, no studies have assessed whether the effects of calcium supplementation on blood lipids are similar between premenopausal and postmenopausal women. OBJECTIVE We assessed the ...

BACKGROUND Advanced oxidation protein products (AOPPs) are acknowledged as a novel marker of oxidation-mediated protein damage. This study aimed to investigate the plasma levels of AOPPs in postmenopausal osteoporotic women, and to determine the relationship between AOPPs accumulation and lumbar bone mineral destiny (BMD) or bone turnover markers. MATERIAL AND METHODS Lumbar BMD was measured ...

With age and menopause there is a shift in adipose distribution from gluteo-femoral to abdominal depots in women. Associated with this redistribution of fat are increased risks of type 2 diabetes and cardiovascular disease. Glucocorticoids influence body composition, and 11beta-hydroxysteroid dehydrogenase type 1 (11betaHSD1) which converts inert cortisone to active cortisol is a putative key m...

Cardiovascular disease (CVD) is one of the leading causes of death worldwide which is more prevalent in women after menopause. Hormonal changes associated with menopause are accountable for dyslipidemic pattern that causes CVD and associated complications. Therefore, the present study was commenced to compare the lipid profile in pre- and postmenopausal women. A descriptive cross-sectional stud...

AIM To evaluate the effects of tamoxifen therapy on plasma lipid profile in patients of breast cancer. METHOD A total of 55 postoperative patients of breast cancer were given tablet tamoxifen 20mg orally daily for 6 months. Estimation of plasma lipid by standard method was carried out in both pre-menopausal and postmenopausal new patients of early stage breast cancer at 0 day, 3rd month and 6...

Estrogen deficiency around menopause can cause growth of abnormal flora leading to infections. The aim of the study was to assess the prevalence of bacterial vaginal infections among the asymptomatic pre and postmenopausal women. High vaginal swab samples were collected and the microorganisms were identified. Their antibiotic susceptibility pattern was noted. Escherichia coli, Staphylococcus au...

Aged people, especially postmenopausal women are at increased risk of metabolic disorders such as obesity, which in turn raises the risk of developing further serious conditions, including diabetes [1,2], cancers, neurological disorders, hypertension, and other cardiovascular diseases [3]. Postmenopausal diabetes is induced by estrogen deficiency, which exacerbates insulin resistance [4,5]. The...

OBJECTIVE Menopause is a physiological life period that potentially affects various organs and systems. Therefore, a wide spectrum of signs and symptoms of eyes may be clinically observed in the postmenopausal period. AIM OF THE STUDY To evaluate the macular, retinal nerve fiber layer (RNFL) and choroidal thickness alterations by using spectral-domain optical coherence tomography (SD-OCT) in ...

BACKGROUND: Osteoporosis is a condition of reduced bone mineral density (BMD) which leads to increased bone fragility and a marked increase in the risk of fractures. Postmenopausal osteoporosis affects women from one to twenty years after menopause. During these years, menopausal hormonal changes cause alterations in the serum levels of various biochemicals which reflect the bone losses. OBJECT...

The incidence of osteoporosis is high in postmenopausal women due to altered estrogen levels and continuous calcium loss that occurs with aging. Recent studies have shown that microRNAs (miRNAs) are involved in the development of osteoporosis. These miRNAs may be used as potential biomarkers to identify women at a high risk for developing the disease. In this study, whole blood samples were col...