AIM Premixed insulin regimens are commonly used for the treatment of patients with type-2 diabetes mellitus (T2DM). However, limited data are available regarding next-step therapy options in cases where premixed insulin fails to provide adequate glycemic control. This 20-week observational study of everyday clinical practice evaluated the efficacy, safety and treatment satisfaction of insulin g...

BACKGROUND The purpose of this study was to determine the efficacy of 5% lidocaine patch in reducing propofol-induced pain and cannula-induced pain. METHODS In a randomized, double-blind study, 126 patients were divided into one of three groups: pretreatment with a 5% lidocaine patch (Lidotop®) and premixed 2 ml of normal saline with 1.5 mg/kg of 1% propofol (Group A); pretreatment with a pla...

Problems of combustion are usually mathematically described by a variabledensity formulation of the Navier-Stokes equations at low Mach number. Finite volume and finite difference methods have been proposed for large-eddy simulation (LES) of variable-density turbulent flows at low Mach number. Finite element methods, which are often better suited for problems in complex geometries, have so far ...

While premixed and nonpremixed microgravity flames have been extensively investigated, the corresponding literature regarding partially premixed flames (PPFs) is sparse. We report the first experimental investigation of burner-stabilized microgravity PPFs. Partially premixed flames with multiple reaction zones are established in microgravity on a Wolfhard–Parker slot burner in the 2.2 s drop to...

Experimental measurements of laser-induced ionization were performed for ethene-air premixed flames operated near the soot inception point. Soot was ionized with a pulsed laser operated at 532 nm. The ionization signal was collected with a tungsten electrode located in the postflame region. Ionization signals were collected by use of both single-electrode and dual-electrode configurations. Earl...

One strategy for reducing US dependence on petroleum is to develop new combustion technologies for burning the fuel-lean mixtures of hydrogen or hydrogen-rich syngas fuels obtained from the gasification of coal and biomass. Fuel-flexible combustion systems based on lean premixed combustion have the potential for dramatically reducing pollutant emissions in transportation systems, heat and stati...

Previous investigations have demonstrated that the roles of fuel stream dilution (FSD) and air stream dilution (ASD) in suppressing CO2-diluted methane flames are strongly influenced by the level of partial premixing. Herein, we compare this influence for both counterflow and coflow laminar non-premixed and partially premixed flames (PPFs) established with various fuels, including methane, ethy...

The interaction of a vortex pair with a premixed flame serves as an important prototype for premixed turbulent combustion. In this study, we investigate the interaction of a counter-rotating vortex pair with an initially flat premixed methane flame. We compare computational solutions obtained using a timedependent, two-dimensional adaptive low Mach number combustion algorithm that incorporates ...

The effects of fuel and air stream dilution (ASD) with carbon dioxide on the suppression of normal and microgravity laminar methane–air partially premixed coflow jet flames were experimentally and numerically investigated. Experiments were conducted both in our normal-gravity laboratory and at the NASA Glenn Research Center 2.2 s drop tower. Measurements included flame topology and liftoff heig...