INTRODUCTION Several single-center studies and meta-analyses have shown that perioperative goal-directed therapy may significantly improve outcomes in general surgical patients. We hypothesized that using a treatment algorithm based on pulse pressure variation, cardiac index trending by radial artery pulse contour analysis, and mean arterial pressure in a study group (SG), would result in reduc...

Objective: The aim of this study was to investigate the effect of pre-treatment with curcumin on metabolic changes induced by two different pathophysiological mechanisms in rats (fructose diet and streptozotocin (STZ)-induced diabetes mellitus). Materials and Methods: Five groups with 10 rats per group were investigated: control group (healthy rats), fructose diet groups without any pre-treatme...

Exercise training improves arterial baroreflex control in heart failure (HF) rabbits. However, the mechanisms involved in the amelioration of baroreflex control are unknown. We tested the hypothesis that exercise training would increase the afferent aortic depressor nerve activity (AODN) sensitivity in ischemic-induced HF rats. Twenty ischemic-induced HF rats were divided into trained (n = 11) ...

OBJECTIVE To evaluate the effect of sarpogrelate for patients with atherosclerotic obliterans (ASO). PATIENTS AND METHODS Patients with ASO were randomly divided into sarpogrelate group (n = 92) and control group (n = 84). The patients in sarpogrelate group received sarpogrelate (100 mg, tid), whereas in control group aspirin (100 mg, qd) was administered orally. The patients were followed up...

introduction: obesity is an independent risk factor in developing cvd, type ii diabetes, and gall bladder disease, different types of cancers, osteoarthritis and mortality. weight gain during adult life, especially during the third and fourth decades, is associated with increased blood pressure. methods: random samples of nearly 1493 men and women aged between 16 to 85 years old were selected f...

[Purpose] This study aimed to investigate the effects of horse-riding exercise on balance, gait, and activities of daily living (ADLs) in stroke patients. [Subjects] Among 20 participants with stroke, 10 were randomly assigned to the experimental group, and 10 were randomly assigned to the control group. The experimental group participated in horse-riding exercise for 30 minutes per day, 5 days...

The effect of pretreatment with the calcium antagonist nimodipine on the pathophysiological events which follow an intracerebral haemorrhage in rats was compared with a similar control group. Cerebral blood flow was higher and the amount of pathologically determined ischaemic damage measured by light microscopy was less in the nimodipine pretreated group. Bloodbrain barrier permeability was inc...

background: endotracheal suctioning (ets) is one of the most common supportive measures in intensive care units (icu). ets may be associated with complications including hypoxia and tachycardia. closed system suctioning (css) decreases the rate of cardiorespiratory complication mainly due to continuation of ventilatory support and oxygenation during procedure. css has questionable efficacy, the...

objective: this study examines the effects of hydrostatic pressure on in vitro maturation (ivm) of oocytes derived from in vitro grown follicles. materials and methods: in this experimental study, preantral follicles were isolated from 12-day-old female nmri mice. each follicle was cultured individually in alpha minimal essential medium (α-mem) under mineral oil for 12 days. then, follicles wer...