We report a case of Eikenella corrodens sepsis associated with CSF pleocytosis in a very low birth weight neonate. A 1000-gram male neonate was born at 27-week gestation due to preterm labor. The patient presented with signs and symptoms of sepsis and was treated for suspected meningitis with intravenous ampicillin and gentamicin for 7 days, with cefotaxime added for three weeks. He had a norma...

The aim of this study was to investigate the prevalence and factors associated with nasal septum injury in preterm infants in the use of noninvasive ventilation. A cross-sectional study with data collection between March and July 2012 and with search for records, interviews with mothers and nasal evaluation of 47 premature in the neonatal unit of a teaching hospital in Recife, Pernambuco, north...

pulmonary haemorrhage (pH) in a sick neonate is a life-threatening complication and is often associated with a high mortality. it is now often seen in extreme preterm and very low birth weight infants who are growth restricted and have received surfactant with significant respiratory distress syndrome. the mainstay of treatment includes ventilation and vigorous resuscitation of a shocked and cr...

BACKGROUND Hypothermia is a major cause of deterioration and death in the neonatal period. Temperature deviations are key signs of illness. OBJECTIVE To determine normal patterns of temperature variation in newborn babies and the influence of external factors. METHODS Abdominal and foot skin temperature were continuously recorded in 27 healthy full term babies during the first two days of l...

abstract background: during health care in the neonatal intensive care unit (nicu), infants undergo extremely painful procedures, which may cause problems, if not controlled, such as changes in the pattern of respiratory rate, heart rate, and blood oxygen saturation. the present study aimed to find the effect of melody on the physiological responses of neonates’ heel stick pain. materials and m...

BACKGROUND In Choma District, southern Zambia, the neonatal mortality rate is approximately 40 per 1000 live births and, although the rate is decreasing, many deliveries take place outside of formal facilities. Understanding local practices during the postnatal period is essential for optimizing newborn care programs. METHODS We conducted 36 in-depth interviews, five focus groups and eight ob...

Respiratory support improvements have aided survival of premature neonates, but infection susceptibility remains a predominant problem. We previously reported that neonatal mice have a rapidly evolving T-cell receptor (TCR) repertoire that impairs CD8+ T cell immunity. To understand the impact of prematurity on the human CD8+ TCR repertoire, we performed next-generation sequencing of the comple...