In this article, we study the periodicity, the boundedness and the global stability of the positive solutions of the following nonlinear difference equation xn+1 = Axn +Bxn−k +Cxn−l +Dxn−σ + bxn−k +hxn−l dxn−k + exn−l , n = 0,1,2, ....., where the coefficients A,B,C,D,b,d,e,h ∈ (0,∞), while k, l and σ are positive integers. The initial conditions x−σ ,...,x−l ,...,x−k, ...,x−1,x0 are arbitrary ...