نتایج جستجو برای: progenitor cell

تعداد نتایج: 1700580  

Journal: :Blood 1992
R A Briddell V C Broudy E Bruno J E Brandt E F Srour R Hoffman

A mouse antihuman monoclonal IgG2a antibody, termed stem cell receptor-1 (SR-1), specific for a determinant of the c-kit ligand receptor (KR), was used as an immunologic probe to analyze KR expression by human bone marrow hematopoietic progenitor cells. Monoclonal antibodies to CD34 and HLA-DR were used in a multicolor staining protocol in conjunction with SR-1 to further define the phenotypes ...

Journal: :Frontiers in bioscience 2016
Ya-Feng Li Xiao Huang Xinyuan Li Ren Gong Ying Yin Jun Nelson Erhe Gao Hongyu Zhang Nicholas E Hoffman Steven R Houser Muniswamy Madesh Douglas G Tilley Eric T Choi Xiaohua Jiang Cong-Xin Huang Hong Wang Xiao-Feng Yang

Caspase-1 activation senses metabolic danger-associated molecular patterns (DAMPs) and mediates the initiation of inflammation in endothelial cells. Here, we examined whether the caspase-1 pathway is responsible for sensing hyperlipidemia as a DAMP in bone marrow (BM)-derived Stem cell antigen-1 positive (Sca-(1+)) stem/progenitor cells and weakening their angiogenic ability. Using biochemical ...

Journal: :Development 1994
S Temple A A Davis

Ventricular zone cells in the developing CNS undergo extensive cell division in vivo and under certain conditions in vitro. The culture conditions that promote cell division have been studied to determine the role that contact with cell membrane associated factors play in the proliferation of these cells. Progenitor cells have been taken from the ventricular zone of developing rat cerebral cort...

Journal: :Development 2014
Jeannine M Basta Lynn Robbins Susan M Kiefer Dale Dorsett Michael Rauchman

The formation of the proper number of functional nephrons requires a delicate balance between renal progenitor cell self-renewal and differentiation. The molecular factors that regulate the dramatic expansion of the progenitor cell pool and differentiation of these cells into nephron precursor structures (renal vesicles) are not well understood. Here we show that Sall1, a nuclear transcription ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1990
P A Scherle K Dorshkind O N Witte

The early stages of hematopoiesis have been difficult to study due to problems in obtaining homogeneous populations of progenitor cells that retain both self-renewal and differentiative capacities. We have developed an in vitro system in which transformation of murine bone-marrow cells with the BCR/ABL oncogene, a gene associated with stem-cell leukemias, leads to the outgrowth of clonal lines ...

2017
Kenyon S. Tweedell

Cell and tissue specific somatic stem cells develop as dynamic populations of precursor cells to discrete tissue and organ differentiation during embryonic and fetal stages and their potential evolves with development. Some of their progeny are sequestered into separate cell niches of tissues as adult somatic stem cells at various times during organ development and differentiation These are div...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه ارومیه - دانشکده منابع طبیعی 1393

تحقیقات مختلف اثبات نموده اند که رشد و محتوای بیوشیمیایی روتیفرها می تواند تحت تاثیر نوع غذا و غلظت مواد غذایی تغییر نماید. ریز جلبک ها به عنوان یکی از منابع غذایی مهم برای کشت روتیفرها به ویژه از لحاظ شاخص های نظیر رشد، بقا، میزان پروتئین، چربی و اسیدهای چرب، ضروری می باشند. لذا تحقیق حاضر جهت مقایسه جلبک خشک (کلرلای پودری) و جلبک های تازه (ایزوکرایسیس گالبانا و نانوکلروپسیس آکولاتا) بر رشد، ت...

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