A stability-indicating, robust, fast, and user friendly reversed-phase high-performance liquid chromatographic (RP-HPLC) assay method has been developed and validated for the analysis of commercial raw material batches of methylparaben, ethylparaben, propylparaben, and butylparaben. These four parabens are widely used as preservatives in pharmaceutical and cosmetic products. Accurate assay valu...

BACKGROUND Human exposure to parabens and other antimicrobial chemicals is continual and pervasive. The hormone-disrupting properties of these environmental chemicals may adversely affect human reproduction. OBJECTIVE We aimed to prospectively assess couples' urinary concentrations of antimicrobial chemicals in the context of fecundity, measured as time to pregnancy (TTP). METHODS In a pros...

phorbiaceae. It is a shrub or small tree reaching 4—5 meters high and native to Thailand, where it is commonly called “Plao phae”. In this paper, we describe the isolation and structure elucidation of newly isolated 3 -(4 -hydroxy-3 ,5 dimethoxyphenyl)-propyl benzoate, 3 -(4 -hydroxyphenyl)propyl benzoate and four known compounds [3 -(4 -hydroxy-3 -methoxyphenyl)-propyl benzoate, poilaneic acid...

Penggunaan metil paraben sebagai pengawet telah banyak digunakan pada berbagai bidang industri, antara lain: industri makanan, kosmetik, dan farmasi dengan batas penggunaan yang diatur oleh setiap negara lembaga. Sampai saat ini, pengukuran umum dilakukan adalah menggunakan spektrofotometri UV/Vis HPLC, namun kedua metode tersebut membutuhkan waktu preparasi analisis cukup lama. Metode alternat...

The single crystal of (-)-gallocatechin-3-O-gallate (GCg) was prepared using a solution containing an equimolecular amount of GCg and (-)-epigallocatechin-3-O-gallate (EGCg) in water. The crystal structure of GCg determined by X-ray crystallographic analysis was monoclinic with the space group P2(1) at 223 K. Offset pi-pi interactions formed between the A and A rings, B and B rings, and gallate...

BACKGROUND Human exposure to phenols, including bisphenol A and parabens, is widespread. Evidence suggests that paternal exposure to environmental chemicals may adversely affect reproductive outcomes. OBJECTIVES We evaluated associations of paternal phenol urinary concentrations with fertilization rate, embryo quality, implantation, and live birth. METHODS Male-female couples who underwent ...

Artificial diets have become important components of rearing systems for insects that are used for research purposes and in commercial production. Because the rearing conditions for insects also provide ideal settings for mold growth, antifungal additives are often used to reduce diet contamination. However, the antifungal agents must not only be effective in mold suppression, they must also be...