نتایج جستجو برای: prostate antigen serum psa test

تعداد نتایج: 1338314  

2015
Taekmin Kwon In Gab Jeong Dalsan You Jun Hyuk Hong Hanjong Ahn Choung-Soo Kim

PURPOSE To investigate the prevalence and clinical significance of incidental prostate fluoro-2-deoxyglucose (FDG) uptake and to evaluate its impact on patient management. MATERIALS AND METHODS Of 47,109 men who underwent FDG positron emission tomography between 2004 and 2014, 1,335 (2.83%) demonstrated incidental FDG uptake in the prostate, with 99 of the latter undergoing prostate biopsy. T...

Journal: :Journal of Drug Delivery and Therapeutics 2021

Background: Prostate cancer is the second most common in men worldwide and leading cause of deaths United States. Obesity has been consistently associated with lower 25-hydroxyvitamin D (25(OH)D) concentrations.
 Objectives: This cross-sectional study aimed to evaluate serum vitamin PSA levels Sudanese Obese Non-Obese prostate (PCa) attending National Cancer Institute.
 Patients Metho...

Journal: :JAMA 2000
K S Ross H B Carter J D Pearson H A Guess

CONTEXT Despite widespread use of serum prostate-specific antigen (PSA) testing to detect prostate cancer, the relative effectiveness of different PSA screening strategies is unknown. OBJECTIVE To compare prostate cancer mortality, PSA testing rates, and biopsy rates using various PSA screening strategies, including the standard strategy of annually testing men aged 50 through 75 years. DES...

Journal: :Radiation diagnostics, radiation therapy 2022

The main protocol for the diagnosis of prostate cancer (PC) is determination level serum prostate-specific antigen (PSA), a digital rectal examination followed by 12-point biopsy PC under guidance transrectal ultrasonography. An isolated increase in PSA may be only reason performance. However, this led to overdiagnosis and overtreatment clinically insignificant disease (40-65% performed biopsie...

Journal: :Clinical oncology research and reports 2022

Background: Prostate cancer is the second most frequent and fifth leading cause of death in men with higher prevalence developed countries. The use biomarkers for prostate can improve diagnosis clinical management patients. Prostate-specific antigen (PSA) widely used to screen there evidence that PSA testing reduces mortality. Objective: In this report we have studied relationship between Gleas...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2005
Patrick J Bastian Ganesh S Palapattu Xiaohui Lin Srinivasan Yegnasubramanian Leslie A Mangold Bruce Trock Mario A Eisenberger Alan W Partin William G Nelson

PURPOSE Hypermethylation of the CpG island at the promoter region of the pi-class glutathione S-transferase gene (GSTP1) is the most common somatic genome abnormality in human prostate cancer. We evaluated circulating cell-free DNA GSTP1 CpG island hypermethylation as a prognostic biomarker in the serum of men with prostate cancer. EXPERIMENTAL DESIGN Prostate cancer DNA GSTP1 CpG island hype...

H.J. Kim, J.H. Phak, W.Ch. Kim,

Background: stereotactic body radiotherapy (SBRT) has emerged as an effective treatment for localized prostate cancer. However, prostate-specific antigen (PSA) kinetics after SBRT has not been well characterized. The objective of the current study is to analyze the rate of PSA decline and PSA nadir following hypofractonated SBRT in localized prostate cancer. Materials and Methods: From 2008...

1999
Mika P. Matikainen Johanna Schleutker Pertti Mörsky Teuvo L. J. Tammela

Positive family history is a significant risk factor for prostate cancer. Improved knowledge of the epidemiology and molecular basis of hereditary prostate cancer has led to a need for counseling and clinical follow-up for men with a positive family history of prostate cancer. However, very little information is available on the efficacy of early screening procedures, such as serum prostate-spe...

Journal: :Environmental Health Perspectives 1993
G Pinholster

Twenty-seven of 152 patients (18%) with progressing hormone resistant prostate cancer had normal serum levels of prostate specific antigen (PSA < 1O jig l-), when referred for secondary treatment. PSA was significantly correlated with the extent of skeletal metastases (R: 0.35) and the levels of hemoglobin (R: -0.19) and serum alkaline phosphatase (R: 0.30). In a multivariate Cox regression ana...

Journal: :Clinical chemistry 2014
Charlotta Sävblom Christer Halldén Angel M Cronin Torbjörn Säll Caroline Savage Emily A Vertosick Robert J Klein Aleksander Giwercman Hans Lilja

BACKGROUND Genetic variants in KLK2 and KLK3 have been associated with increased serum concentrations of their encoded proteins, human kallikrein-related peptidase 2 (hK2) and prostate-specific antigen (PSA), and with prostate cancer in older men. Low PSA concentrations in seminal plasma (SP) have been associated with low sperm motility. To evaluate whether KLK2 and KLK3 genetic variants affect...

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