Hydrogen sulfide (H2S) has long been recognized as a putrid, toxic gas. However, result of intensive biochemical research in the past two decades, H2S is now considered to be third gasotransmitter alongside nitric oxide (NO) and carbon monoxide (CO) mammalian systems. H2S-producing enzymes are expressed all organs, playing an important role their physiology. In kidney, critical regulator vascul...

1. When Escherichia coli was grown exponentially in a defined medium at 35 degrees , the rate of protein breakdown was initially rapid, but decreased to 0.6%/hr. after about 30min. The latter rate was maintained for at least 3.5hr. 2. The initial rapid rate may have been due to the presence of a small protein fraction (about 1%) that was degraded with a half-life of 13min. 3. The rate of protei...

We have examined the effects of a surgical level of thiopental anesthesia in adult male rats on local rates of cerebral protein synthesis with the quantitative autoradiographicl-[1-14C]leucine method. The relative contribution of leucine derived from protein breakdown to the intracellular precursor amino acid pool for protein synthesis was found to be statistically significantly decreased in th...

Aim: This study aimed to investigate the effect of non-synonymous SNPs (nsSNPs) Glucagon-like peptide-1 Receptor (GLP-1R) gene in protein function and structure using different computational software. Introduction: The GLP1R provides necessary instruction for synthesis insulin hormones which is needed glucose catabolism. Polymorphisms this are associated with diabetes. an important drug target ...

Long-term starvation induces an increase in the protein degradation of skeletal muscle in human and laboratory animals.t'9) Rats subjected to refeeding have demonstrated a reduction in the rate of muscle pretein degradation.'・3・5・6・S・") This decrease in degradation due to refeeding is associated with changes in the plasma concentration of many hormones such as insulin, insulinIike growth factor...