Background and Aims: Influenza A virus of Orthomyxoviridae family is able to create pandemic influenza. Vaccination is the most effective way to prevent influenza virus infection. Matrix protein 2 (M2) is a homotetramer ion channel with 97 amino acids length and highly conserved among influenza viruses and is considered for development of a universal influenza vaccine. Materials and Methods: We...

2. Computational Genomics and Proteomics . . . . . . . . . . . . . . . . 3 2.1. DNA Sequencing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2.2. DNA and RNA Structures . . . . . . . . . . . . . . . . . . . . . . 3 2.3. Protein Sequencing . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2.4. Protein Structure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2.5. ...

One of the most commonly observed surface structures on the prokaryotic cell envelopes is monomolecular crystalline array of proteinaceous subunits termed Surface Layers or S-layers. Due their self assembly ability and the highly ordered, regular structure down to the nanometer scale, S-layers were demonstrated to possess a great potential for nanobiotechnological applications. Some probiotic b...

objective(s) tuberculosis (tb) is the leading cause of mortality among the infectious diseases, especially in developing countries. one of the main goals in tuberculosis research is to identify antigens which have the ability of inducing cellular and/or humoral immunity in order to use them in diagnostic reagents or vaccine design. the aim of this study was to clone and express the tb'0.4 ...