The study was aimed to investigate essential oil chemical composition (gas chromatography/flame ionization detection [GC-FID] and gas chromatography/mass spectrometry [GC-MS]) and antioxidant (1,1-diphenyl-2-picrylhydrazyl free radical (DPPH) and 2,2'-azinobis-3-ethylbenzothiazoline-6-sulphonate [ABTS] assays) and antimicrobial (Gram-positive and Gram-negative bacteria, fungi, and yeast) activi...

Background: Pulegone (PGN) is a clear colorless oily liquid, which is widely used in different areas for flavoring foods, drinks, and dental products. There are several reports indicating that the metabolites of the PGN affect cytochrome-P450 family expression and activities. The cytochromes-P450 (cyp19) are involved in Leydig Cells aromatization. Therefore, present study was performed in order...

there is a growing interest in food industry to replace the synthetic chemicals by the natural products with bioactive properties from plant origin. the aim of this study was to determine the chemical composition of mentha pulegium essential oil and to characterize the antimicrobial activities of the essential oil. the essential oil of mentha pulegium was analyzed by gc-ms. the evaluation of th...

Objectives. The stratum corneum (SC) remains an obstacle to the passage of drugs applied topically. Severalinvestigations have focused on enhancing penetration through SC by integrating permeationenhancers (PE) into drug formulation. Terpenes are among PE utilized in formulations and categorized regulatory bodies as generally recognized safe (GRAS). This study aimed comparatively analyze skin p...

The effect and responses to drought stress were analyzed in Quercus ilex L. seedlings using a nontargeted metabolomic approach, implementing the approaches of previous studies which other -omics platforms, transcriptomics, proteomics employed. This work aimed characterize Q. leaf metabolome, determining possible mechanisms molecular markers tolerance identifying putative bioactive compounds. Si...

Peppermint (Mentha × piperita L.) was transformed with various gene constructs to evaluate the utility of metabolic engineering for improving essential oil yield and composition. Oil yield increases were achieved by overexpressing genes involved in the supply of precursors through the 2C-methyl-D-erythritol 4-phosphate (MEP) pathway. Two-gene combinations to enhance both oil yield and compositi...

The aim of the present study was to determine the chemical structures of the isolated compounds, the essential oil and fatty acid compositions of Mentha longifolia subsp. noeana with their biological activities. Ursolic acid (1), uvaol (2), stigmast-5-ene-3-yl formate (3), stigmast-5-en-3-one (4), -sitosterol (5), bis(2ethylhexyl) benzene-1,2-dicarboxylate (6), hexacosyl (E)-ferulate (7) and ...

The application of biocatalysis for the asymmetric reduction of activated C=C is a powerful tool for the manufacture of high-value chemical commodities. The biocatalytic potential of "-ene" reductases from the Old Yellow Enzyme (OYE) family of oxidoreductases is well-known; however, the specificity of these enzymes toward mainly small molecule substrates has highlighted the need to discover "-e...

This study aims to the impact of environmental stresses on chemical compositions essential oils and content secondary metabolites plants most used by rural population: Thymus vulgaris, Mentha pulégium Rosmarinus officinalis. The results indicate that percentage increased in second year when temperature water pressure 50%. Specifically, coumarin from 3.94% 9.23%, saponins 6.17% 7.78%, tannins 2....