This study explored the effect of focal cerebral contusion on the expression of ApoE and S-100, and its significance in determining the time of brain injury. Based on a rat model of cerebral contusion, immunohistochemistry was used to analyze the expressions of S-100 and ApoE at different time points after injury. Thirty minutes following cerebral contusion, ApoE protein expression was signific...

To the Editor:—The recent article by Thille et al. and the accompanying editorial by Rouby discuss the effects of positive end-expiratory pressure (PEEP) on pulmonary recruitability in patients with adult respiratory distress syndrome (ARDS). Thille et al. found that alveolar recruitment was similar in pulmonary and extrapulmonary ARDS and concluded that PEEP levels should not be determined bas...

INTRODUCTION Post-traumatic pulmonary pseudocyst is an uncommon cavitary lesion of the lung and develops after blunt chest trauma and even more rarely following penetrating injuries. It is generally seen in young adults presenting with cough, chest pain, hemoptysis, and dyspnea. Post-traumatic pulmonary pseudocyst should be included in the differential diagnosis of cavitary pulmonary lesions. W...

The objective of this study was to investigate early changes in oxygenation by means of the multiple inert gas elimination technique and in coagulation by means of thromboelastography (TEG) after right-sided pulmonary contusion (PC) in swine. Anesthetized swine (group 1; n = 8) sustained a right-chest PC by a captive-bolt stunner. Multiple inert gas elimination technique, TEG, and thoracic comp...

A 5-year-old male with a history of frequent upper respiratory infections presented following a motor vehicle crash as an unrestrained, ejected passenger. CT of the chest and abdomen showed a small liver laceration, multifocal peripheral lung opacities ( fig. 1 , black arrows) and extensive lung laceration ( fig. 1 , white arrow). The patient required supplemental oxygen, but no surgical interv...

A myocardial contusion refers to a bruise of the cardiac muscle, the severity of which can vary depending on the severity of the injury and when the injury occurs. It is a major cause of rapid death which happens after blunt chest trauma and should be suspected at triage in the emergency department. We demonstrated that suspected myocardial contusion patients who have normal electrocardiograms ...