PURPOSE To retrospectively compare thin-section computed tomographic (CT) scores obtained with five scoring systems for assessment of pulmonary disease in children with cystic fibrosis and to determine additional value of bronchial and arterial dimension measurements. MATERIALS AND METHODS Scores obtained with five thin-section CT scoring systems were compared. A score of 0 indicated the abse...

Background Chronic obstructive pulmonary disease (COPD), the third leading cause of death worldwide, is often underdiagnosed. Purpose To develop machine learning methods to predict COPD using chest radiographs and a convolutional neural network (CNN) trained with near-concurrent function test (PFT) data. Comparison made natural language processing (NLP) associated radiologist text reports. ...

asthma management is a major concern because some asthmatic patients either do not respond or else hardly respond to treatment. therefore in the present study, an attempt has been made to determine the predictors of treatment response in asthmatic patients. thirty six asthmatic adults including 13 male and 23 female were studied dur¬ing a 3 month treatment period. asthma symptom score (ss) and ...

OBJECTIVE Pulmonary artery smooth muscle cells (PA-SMCs) in pulmonary arterial hypertension (PAH) show similarities to cancer cells. Due to the growth-suppressive and pro-apoptotic effects of p53 and its inactivation in cancer, we hypothesized that the p53 pathway could be altered in PAH. We therefore explored the involvement of p53 in the monocrotaline (MCT) rat model of pulmonary hypertension...

Chronic obstructive pulmonary disease (COPD) is a long-term, irreversible, and progressive respiratory that often leads to lung function decline. Pulmonary tests (PFTs) provide valuable information for diagnosing COPD; however, they are underutilised in clinical practice, with only subset of test values being used decision making. The final diagnosis requires combining PFT results patient infor...

High resolution computed tomography (HRCT) was recently demonstrated to be as good as open lung biopsy for the diagnosis of pulmonary involvement in patients with scleroderma. Nevertheless, in view of its price and related irradiation, HRCT cannot be recommended as a screening test. Serum III procollagen (sPIIINP) is an aminopropeptide of type III collagen, which is released during conversion i...

OBJECTIVE To investigate the relationships between spinal mobility, pulmonary function, structural change of the spine, pain, fatigue, and quality of life (QOL) in patients with ankylosing spondylitis (AS). METHODS Thirty-six patients with AS were recruited. Their spinal mobility was examined through seven physical tests: modified Schober test, lateral bending, chest expansion, occiput to wal...

The present study was undertaken to assess the difference between the normal predicted value and observed value of pulmonary function test (PFT) amongst the asthmatic patients and also to compare the aforesaid observed values between male and female asthmatic patients. Clinically diagnosed cases (male 62, female 75) of bronchial asthma attending medical out patient department of Nepal Medical C...

BACKGROUND COPD is a major cause of morbidity in smokers. The COPD assessment test (CAT) is a validated test for evaluation of COPD impact on health status. CAT is not a diagnostic test and pulmonary function test (PFT) still remains the most important diagnostic test. However, its predictive value for evaluation of disease impact is weak. The purpose of this study was to determine the relation...

INTRODUCTION Cell count in induced sputum is a noninvasive biomarker to assess airway inflammation phenotypes. Accordingly, sputum cell counts are extensively used in the treatment of asthma and COPD. Nevertheless, the clinical application of sputum cell counts in patients with asthma-COPD overlap (ACO) remains elusive. The aim of this study was to investigate sputum cell counts in patients wit...