Persistent multiple pulmonary nodules were observed on the chest X ray of a nonimmunocompromised woman 6 months after she was treated with acyclovir for a varicella-related myelitis without respiratory symptoms. Early antiviral therapy given for varicella infections might decrease the intensity of clinical symptoms without actually preventing the occurrence of varicella-zoster virus-related les...

Lymphomatoid granulomatosis is an uncommon disorder that can present as multiple pulmonary nodules. Systemic manifestations such as fever, weight loss, skin lesions, and other organ involvement may occur. The clinical presentation of lymphomatoid granulomatosis can mimic infectious diseases (eg, tuberculosis), vasculitis, or metastatic malignancies.1 Lymphomatoid granulomatosis should be consid...

Pulmonary nodule detection and characterization continue to improve with technological advancements. The noninvasive methods available for assisting in nodule detection and for characterizing nodules as benign, malignant, or indeterminate will be discussed. Evidence-based guidelines will be reviewed to help guide the appropriate management of pulmonary nodules.

INTRODUCTION Video-assisted thoracic surgery (VATS) has become routine and widely accepted for the removal of solitary pulmonary nodules of unknown etiology. Thoracosopic techniques continue to evolve with better instruments, robotic applications, and increased patient acceptance and awareness. Several techniques have been described to localize peripheral pulmonary nodules, including pre-operat...

BACKGROUND Pulmonary nodules are spherical radiographic opacities that measure up to 30 mm in diameter. Nodules are extremely common in clinical practice and challenging to manage, especially small, "subcentimeter" nodules. Identification of malignant nodules is important because they represent a potentially curable form of lung cancer. METHODS We developed evidence-based clinical practice gu...

Background: Accurate intraoperative localization of the nodules was key point sub-lobectomy resection. Percutaneous computed tomography (CT)-guided hook-wire most widely used method to locate pulmonary nodules, however, it associated with high rates pneumothorax and parenchymal hemorrhage. In recent years, surgeons were continuously seeking innovative approaches cover limitations CT-guided hook...

OBJECTIVE We wanted to describe the findings of simple pulmonary eosinophilia with using 18 fluorodeoxyglucose (FDG) positron emission tomography (PET). MATERIALS AND METHODS We analysed the findings of 14 patients who underwent thoracic computed tomography (CT) and PET, and then they were subsequently proven to have simple pulmonary eosinophilia. PET studies were performed in four patients w...

Pulmonary meningothelial-like nodules are benign lesions that are often incidentally detected in surgically resected lung tissue. These nodules are usually asymptomatic and single. Rarely, they present as diffuse micronodules similar to the miliary pattern seen in tuberculosis or metastatic cancer. While diffuse meningothelial-like micronodules are usually benign, it is important to include thi...

Pulmonary nodules are defined by a size 3 cm, whereas a lung mass is defined by a size 3 cm. Excellent clinical practice guidelines for evaluating patients with a solitary pulmonary nodule for possible lung cancer have been published.1,2 The appearance of pulmonary nodules in an immunocompromised host is a common clinical problem that falls outside the scope of published algorithms. Because the...

To cite: Callister MEJ, Baldwin DR, Akram AR, et al. Thorax 2015;70: ii1–ii54. SUMMARY OF RECOMMENDATIONS This guideline is based on a comprehensive review of the literature on pulmonary nodules and expert opinion. Although the management pathway for the majority of nodules detected is straightforward it is sometimes more complex and this is helped by the inclusion of detailed and specific reco...