OBJECTIVE To evaluate the cardiotoxicity of LV5FU2 regimen (bolus plus infusional 5-fluorouracil/folinic acid) treatment by non-invasive methods such as echocardiography, plasma troponin I (TnI) level, QT interval and QT dispersion on ECG. METHODS Twenty-two patients with gastrointestinal cancer who received LV5FU2 chemotherapy were evaluated prospectively during 12 cycles of chemotherapy. Pl...

OBJECTIVE T wave peak to T wave end (TpTe) interval and TpTe/QT have been accepted as predictors of ventricular arrythmia. In this study our aim is to investigate the effect of metabolic syndome on these parameters in patients with angiographically normal coronary arteries. MATERIALS AND METHODS Thirty patients with metabolic syndrome (4 male, mean age 52±7.8 years) and twenty patients withou...

BACKGROUND AND OBJECTIVES In our study we aimed to investigate the effect of bupivacaine and levobupivacaine on QT, corrected QT (QTc), and P wave dispersion durations during spinal anesthesia in cesarean section. METHODS Sixty parturients scheduled for elective cesarean section in ASA I-II risk groups were included in the study. Baseline electrocardiographic (ECG) records of the patients wer...

Issue 21 - Jean-Luc Godard once observed of Bertrand Tavernier that they shared a common origin: as children “the Libération and the Cinémathèque” came age in turbulent 1960s (qtd. A Journey Through French Cinema (Voyage à travers le cinéma français, Tavernier, 2016)). who died March this year, is an appropriate filmmaker to commemorate Introduction issue Alphaville dedicated themes me...

OBJECTIVES To examine whether the favourable effects on endothelial function, vascular angiotensin converting enzyme (ACE) activity, cardiac remodelling, autonomic function, and QT intervals of spironolactone in combination with ACE inhibitor also occur in patients with New York Heart Association class I-II congestive heart failure (CHF) taking optimal treatment (including beta blockers). MET...

Sudden cardiac death is a dramatic, undesirable event that can often result from cardiomyopathies. To investigate the validity of the QTdispersion (QTd) in revealing regional heterogeneity of repolarisation, with consequent possibility of sudden death, we evaluated ECGs of patients affected by Becker muscular dystrophy (BMD). This is an X linked recessive muscular dystrophy caused by dystrophin...

In the early 1990s, when activists first accused apparel and footwear companies like Nike, Wal-Mart, and the Gap of profiting from exploitation, child labor, and the suppression of labor rights in their supply chains, most companies responded by denying responsibility. Confronted in 1992 with images of child labor in a Bangladeshi factory, Wal-Mart’s CEO famously dismissed them, telling Datelin...

Results: BAI scores (26.6 ± 11.8 vs. 3.4 ± 3.3, p< 0.001) and BDI scores (12.6 ± 4 vs. 3.7 ± 4.5, p< 0.001) were signifi cantly higher in the patient group compared to the controls. P wave dispersion (Pd) [50.0 ± 17.5 miliseconds (ms) vs. 23.4 ± 7.7 ms, p< 0.001] and mean QT dispersion (QTd) (50.5 ± 18.1 ms vs. 28.3 ± 11.4 ms, p< 0.001) signifi cantly increased in the GAD patient group compared...