نتایج جستجو برای: rabeprazole
تعداد نتایج: 497 فیلتر نتایج به سال:
The aim of this study was to assess the efficacy of esomeprazole-based triple therapy compared with rabeprazole-based triple therapy according to CYP2C19 genotype and clarithromycin susceptibility status for first-line eradication therapy of Helicobacter pylori (H. pylori) in Japan. We enrolled 219 H. pylori-infected patients, and randomly allocated patients to the EAC group (esomeprazole 20 mg...
Article history: Received on: 07/09/2013 Revised on: 19/09/2013 Accepted on: 23/11/2013 Available online: 29/11/2013 This work presents two simple and direct spectrophotometric methods for determination of rabeprazole sodium (RB) through charge transfer complexation reactions. The first method is based on the reaction of the drug with p-chloranilic acid (p-CA) in acetonitrile to give a red colo...
The aim of the study was to prepare and evaluate bucco-adhesive tablets of rabeprazole sodium that avoid gastric degradation and first pass metabolism, thereby increasing the drug bioavailability and onset of action. The drug, rabeprazole sodium, belongs to a class of antisecretory compounds. In the present work, different ratios of Gantrez MS 955 along with HPMC K4M were studied to give bioadh...
OBJECTIVES The American Food and Drug Administration has suggested that proton pump inhibitors increase the international normalized ratio (INR) when used concomitantly with warfarin, by being metabolized by cytochrome P450 2C19. We therefore reviewed patients taking warfarin. METHODS AND RESULTS Two hundred and forty patients who took warfarin after surgery were divided into two groups: Grou...
Background/Aims The ability of endoscopic submucosal dissection (ESD) to resect large early gastric cancers (EGCs) results in the need to treat large artificial gastric ulcers. This study assessed whether the combination therapy of rebamipide plus a proton pump inhibitor (PPI) offered benefits over PPI monotherapy. Methods In this prospective, randomized, multicenter, open-label, and comparat...
BACKGROUND Non-erosive reflux disorder, which represents more than 60% of gastro-esophageal reflux disorders, lacks objective parameters for diagnosis. The purpose of this study was to evaluate the correlation between non-erosive minimal lesions at the lower esophagus and gastro-esophageal reflux disorder. METHODS Patients were asked to answer a symptom questionnaire. The endoscopic findings ...
BACKGROUND/AIMS To evaluate the adjuvant effects of N-acetylcysteine (NAC) on first-line sequential therapy (SQT) for Helicobacter pylori infection. METHODS Patients with H. pylori infections were randomly assigned to receive sequential therapy with (SQT+NAC group, n=49) or without (SQT-only group, n=50) NAC. Sequential therapy consisted of rabeprazole 20 mg and amoxicillin 1 g for the first ...
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