Early continuous hormonal treatment, inhibiting TSH secretion, reduces the volume of recent homogeneous goiters. This treatment is usually well tolerated, but can induce thyrotoxicosis in subjects with blunted response of TSH to TRH stimulation before treatment. Surgery is used for large goiters, compressive goiters or suspicion of cancer and after failure of the hormonal treatment. In all case...

Cancer screening and surveillance programmes and the use of sophisticated imaging tools such as positron emission tomography-computed tomography (PET-CT) have increased the detection of impalpable lesions requiring imaging guidance for excision. A new technique involves intra-lesional insertion of a low-activity iodine-125 ((125)I) seed and detection of the radioactive signal in theatre using a...

Isotope dilution mass spectrometry (IDMS) is used extensively at NBS in the certification of elemental concentrations in Standard Reference Materials. It is regarded at NBS as a "definitive method," that is, a method of proven high accuracy. Since the theme of this symposium is accuracy in trace element analysis, it is appropriate to review the role IDMS plays in accurate inorganic analysis. Th...

The primary treatment of thyroid carcinoma is surgery and the outcome depends on its extent. The post-operative management alternatives in thyroid carcinoma include thyroid hormone, radio-iodine ablation (I-131 Na), external beam radiation therapy (EBRT) and occasionally adjuvant chemotherapy. This retrospective study analyzes the managements of 153 patients (102, 51), age range 10-96 yea...

Patients in the Birmingham region who are treated with radio-iodine are kept under continued surveillance by means of a follow-up system, which effects periodic screening for hypothyroidism. In this follow-up system, which is described elsewhere (Barker and Bishop, 1969), the serum protein bound iodine (PBI) is measured at intervals of 21 months. Nine months before serum PBI measurement is due ...

the primary treatment of thyroid carcinoma is surgery and the outcome depends on its extent. the post-operative management alternatives in thyroid carcinoma include thyroid hormone, radio-iodine ablation (i-131 na), external beam radiation therapy (ebrt) and occasionally adjuvant chemotherapy. this retrospective study analyzes the managements of 153 patients (102, 51), age range 10-96 years, me...

INTRODUCTION In a previous report, we have shown that antisera prepared against a mouse tumor (the Wagner osteogenic sarcoma) contained antibodies capable of localizing in vivo in the mouse tumor, while antisera prepared against normal mouse organs did not. We had already shown that antisera prepared against normal rat (2,4, 7, 9,10) and mouse tissues (5) contained antibodies capable of localiz...