The effect of cortisone and endotoxin, singly and in combination, on ribonucleic acid (RNA) synthesis in livers of adrenalectomized mice was determined. This was accomplished by measuring the incorporation either of inorganic (32)P or of (14)C-orotic acid into the RNA. Under similar conditions, the effect of these agents on the rate of protein synthesis was examined with the use of (14)C-leucin...

Hyperpolarized Kr surface quadrupolar relaxation (SQUARE) generates MRI contrast that was previously shown to correlate with surface-to-volume ratios in porous model surface systems. The underlying physics of SQUARE contrast is conceptually different from any other current MRI methodology as the method uses the nuclear electric properties of the spin I 1⁄4 9/2 isotope Kr. To explore the usage o...

THIS REVIEW is an attempt to answer two questions. First, are there any isotope technics available at the present time that are really useful in the care of patients? And second, what will be the role of isotope technics in clinical cardiology a few years from now? Historical Review The use of isotopes in clinical cardiology was introduced by Blumgart, Yens, and Weiss, who used radium C and a c...

Previous investigations on the structure and growth of long bones have been made by many and varied techniques. As early as 1727 Hales first demonstrated experimentally by drilling holes to act as markers that in the growing bone the markers always remained at the same distance apart and that there was therefore no interstitial growth. This has been subsequently confirmed by many workers using ...

I N THIS study two of the radioactive isotopes of chlorine, Cl36 (half life 400,000 years) and C138 (half life 38 minutes) have been used in an effort to establish more definitively than has been done previously the relationships, in the dog, of the chloride space to the volumes of distribution of sodium, bromide and inulin. The first measurements of the radioactive chloride space in dogs were ...

Experimental values for the viscosity of radioactive hydrogen isotope tritium (T2) are currently unavailable in literature. The value this material property over a wide temperature range is interest applications fields fusion and neutrino physics, as well to test ab initio calculations. As gas, requires careful experiment design ensure safe environmental contamination–free measurements. In cont...